Table 1

Study design and dosing schedule

GroupNDoses and administration schedule
3H9, 0.6 mg/kg IVVehicle, SC dailyALX-0681, 2.5 mg/kg SC daily
Control animals d 1, 3, 5, 7, 9 d 1-11  
Preventive ALX-0681–treated animals d 1 and 3  d 1-5 
Therapeutic ALX-0681–treated animals d 1, 3, 5, 7, 9 d 1-4 d 5-11 
GroupNDoses and administration schedule
3H9, 0.6 mg/kg IVVehicle, SC dailyALX-0681, 2.5 mg/kg SC daily
Control animals d 1, 3, 5, 7, 9 d 1-11  
Preventive ALX-0681–treated animals d 1 and 3  d 1-5 
Therapeutic ALX-0681–treated animals d 1, 3, 5, 7, 9 d 1-4 d 5-11 

Table shows an overview of the timing of injections in the different study groups.

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