Table 4

Multivariate analysis of the BPM in the training and the validation sets of patients with DLBCL

Overall survival
Event-free survival
Hazard ratio95% CIPHazard ratio95% CIP
Training set       
    BPM score 2-3 4.3 2.1-9.0 .0001 3.6 1.9-6.6 < .0001 
    IPI score 3-5 2.7 1.3-5.3 .0052  1.1-3.8 .018 
Validation set       
    BPM score 2-3 5.2 2.2-12.3 .0002 3.5 1.7-7.4 .0008 
    IPI score 3-5 3.5 1.6-7.9 .0026 2.6 1.2-5.4 .011 
Overall survival
Event-free survival
Hazard ratio95% CIPHazard ratio95% CIP
Training set       
    BPM score 2-3 4.3 2.1-9.0 .0001 3.6 1.9-6.6 < .0001 
    IPI score 3-5 2.7 1.3-5.3 .0052  1.1-3.8 .018 
Validation set       
    BPM score 2-3 5.2 2.2-12.3 .0002 3.5 1.7-7.4 .0008 
    IPI score 3-5 3.5 1.6-7.9 .0026 2.6 1.2-5.4 .011 

BPM indicates biologic prognostic model; DLBCL, diffuse large B-cell lymphoma; CI, confidence interval; and IPI, International Prognostic Index.

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