Genes up-regulated in CXCR1− subset compared with those in the CXCR1+ subset
| Fold change . | Gene symbol . | Gene name . | Description . |
|---|---|---|---|
| 17.75 | GZMK | Granzyme K (granzyme 3; tryptase II) | Cytolytic serine protease |
| 6.88 | IL-7R | Interleukin 7 receptor | Interleukin 7 receptor α chain |
| 6.69 | IL-7R | Interleukin 7 receptor | Interleukin 7 receptor α chain |
| 5.84 | VCAM1 | Vascular cell–adhesion molecule 1 | Cell-surface sialoglycoprotein (cell-adhesion molecule) |
| 4.76 | NELL2 | NEL-like 2 (chicken) | Cytoplasmic glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)–like domains |
| 4.70 | RCAN3 | RCAN family member 3 | Regulator of calcineurin protein |
| 4.56 | SPRY1 | Sprouty homolog 1 (Drosophila) | Regulator of EGFR signaling |
| 4.48 | SPRY2 | Sprouty homolog 2 (Drosophila) | Regulator of EGFR signaling |
| 4.27 | CDCA7 | Cell division cycle–associated 7 | c-Myc–responsive transcription regulator |
| 3.83 | GPR183 | G protein–coupled receptor 183 | G protein–coupled receptor |
| 3.20 | DUSP4 | Dual specificity phosphatase 4 | Dual specificity protein phosphatase subfamily |
| 2.96 | RCAN3 | RCAN family member 3 | Regulators of calcineurin protein |
| 2.71 | TBC1D4 | TBC1 domain family, member 4 | Regulator of Rab GTPase activity |
| 2.62 | CAMK4 | Calcium/calmodulin-dependent protein kinase IV | Ca2+/calmodulin-dependent protein kinase |
| Fold change . | Gene symbol . | Gene name . | Description . |
|---|---|---|---|
| 17.75 | GZMK | Granzyme K (granzyme 3; tryptase II) | Cytolytic serine protease |
| 6.88 | IL-7R | Interleukin 7 receptor | Interleukin 7 receptor α chain |
| 6.69 | IL-7R | Interleukin 7 receptor | Interleukin 7 receptor α chain |
| 5.84 | VCAM1 | Vascular cell–adhesion molecule 1 | Cell-surface sialoglycoprotein (cell-adhesion molecule) |
| 4.76 | NELL2 | NEL-like 2 (chicken) | Cytoplasmic glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)–like domains |
| 4.70 | RCAN3 | RCAN family member 3 | Regulator of calcineurin protein |
| 4.56 | SPRY1 | Sprouty homolog 1 (Drosophila) | Regulator of EGFR signaling |
| 4.48 | SPRY2 | Sprouty homolog 2 (Drosophila) | Regulator of EGFR signaling |
| 4.27 | CDCA7 | Cell division cycle–associated 7 | c-Myc–responsive transcription regulator |
| 3.83 | GPR183 | G protein–coupled receptor 183 | G protein–coupled receptor |
| 3.20 | DUSP4 | Dual specificity phosphatase 4 | Dual specificity protein phosphatase subfamily |
| 2.96 | RCAN3 | RCAN family member 3 | Regulators of calcineurin protein |
| 2.71 | TBC1D4 | TBC1 domain family, member 4 | Regulator of Rab GTPase activity |
| 2.62 | CAMK4 | Calcium/calmodulin-dependent protein kinase IV | Ca2+/calmodulin-dependent protein kinase |
Genes up-regulated more than 2-fold in all individuals, with statistical significance at P < .01.