Incidence rate of thrombosis and bleeding according to response criteria in 261 PV patients treated with HU
| Type of sustained response . | Follow-up person-years . | Thrombosis . | Bleeding . | ||||
|---|---|---|---|---|---|---|---|
| No. of events . | Incidence rate (× 1000 person-years) . | P . | No. events . | Incidence rate (× 1000 person-years) . | P . | ||
| ELN response | |||||||
| Yes | 777.3 | 22 | 28.3 | .5 | 10 | 12.8 | .5 |
| No | 949.0 | 33 | 34.7 | 16 | 16.8 | ||
| Hematocrit < 0.45 L/L | |||||||
| Yes | 1101 | 36 | 32.7 | .8 | 16 | 14.5 | .8 |
| No | 625 | 19 | 30.4 | 10 | 16.0 | ||
| WBC count < 10 × 109/L | |||||||
| Yes | 1484.6 | 45 | 30.3 | .4 | 21 | 14.1 | .4 |
| No | 241.7 | 10 | 41.4 | 5 | 20.7 | ||
| Platelet count < 400 × 109/L | |||||||
| Yes | 1223.5 | 32 | 26.1 | .04 | 12 | 9.8 | .009 |
| No | 502.8 | 23 | 45.7 | 14 | 27.8 | ||
| Type of sustained response . | Follow-up person-years . | Thrombosis . | Bleeding . | ||||
|---|---|---|---|---|---|---|---|
| No. of events . | Incidence rate (× 1000 person-years) . | P . | No. events . | Incidence rate (× 1000 person-years) . | P . | ||
| ELN response | |||||||
| Yes | 777.3 | 22 | 28.3 | .5 | 10 | 12.8 | .5 |
| No | 949.0 | 33 | 34.7 | 16 | 16.8 | ||
| Hematocrit < 0.45 L/L | |||||||
| Yes | 1101 | 36 | 32.7 | .8 | 16 | 14.5 | .8 |
| No | 625 | 19 | 30.4 | 10 | 16.0 | ||
| WBC count < 10 × 109/L | |||||||
| Yes | 1484.6 | 45 | 30.3 | .4 | 21 | 14.1 | .4 |
| No | 241.7 | 10 | 41.4 | 5 | 20.7 | ||
| Platelet count < 400 × 109/L | |||||||
| Yes | 1223.5 | 32 | 26.1 | .04 | 12 | 9.8 | .009 |
| No | 502.8 | 23 | 45.7 | 14 | 27.8 | ||