Table 2

Multivariate analysis of initial factors predicting survival in 261 patients with PV treated with HU

HR95% CIP
Age > 65 y 3.0 1.6-5.9 .001 
Male sex 2.3 1.2-4.3 .008 
Cardiovascular risk factors* 1.6 0.8-3.2 .2 
History of thrombosis 1.4 0.8-2.6 .2 
Hematologic values at diagnosis    
    Hemoglobin > 180 g/L 0.7 0.4-1.3 .2 
    Leukocyte count > 10 × 109/L 2.9 1.5-5.9 .002 
    Platelet count > 500 × 109/L 0.9 0.5-1.8 .9 
HR95% CIP
Age > 65 y 3.0 1.6-5.9 .001 
Male sex 2.3 1.2-4.3 .008 
Cardiovascular risk factors* 1.6 0.8-3.2 .2 
History of thrombosis 1.4 0.8-2.6 .2 
Hematologic values at diagnosis    
    Hemoglobin > 180 g/L 0.7 0.4-1.3 .2 
    Leukocyte count > 10 × 109/L 2.9 1.5-5.9 .002 
    Platelet count > 500 × 109/L 0.9 0.5-1.8 .9 
*

Presence of either diabetes, arterial hypertension, smoking, or hypercholesterolemia.

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