Table 9 Relationship of TTR to specific... | American Society of Hematology

Table 9

Relationship of TTR to specific PRα/LBD⁺ and ACA, age, and FLT3 mutations

Patient no.	TTR, days	Days of maintenance	PRα/LBD⁺	ACA	Age	FLT3 mutation
14	134	0	Y208N†	None	1§	ITD⁺
32	175	0	R217H†	NA	4§	ITD⁺
39	218	107	R217H†	NA	11§	—
5	265	118	N	t(3;11)‡	11§	—
10	265	130	N	add(22p)‡ add(7q)‡	3§	D835⁺
22	309	179	Δ412–414	NA	44	—
30	339	196	I273F	NA	43	ITD⁺
9	359	231	G289E	add(6)(q21)‡	35	—
17	363	218	R276Q and L224P†	None	65	ITD⁺ and D835⁺‡
7	401	279	G289E	+8	42	ITD⁺
11	520	365	T285A	None	28	—
27	528	365	R276Q	NA	32	—
37	546	365	G289R	NA	15	—
15	644*	365	R272Q	t(4;5)‡	13§	—
4	655*	365	N	i(8)(q10)‡	31	—
20	657*	365	R276W	+8	64	—
12	678*	365	N	+8‡	31	—
8	682*	365	G289R	+8 and 3ACA‡	49	—
40	686*	365	S287W	NA	49	—
3	718*	365	N	t(10;11)	17	—
1	728*	0	S287L	t(4;5),del(20)‡	64	—
6	874*	365	Δ207–208†	t(3;12)‡	18	—
19	1057*	365	N	ider(17q)	36	—
31	1431*	365	K238E†	NA	32	—

Patient no.	TTR, days	Days of maintenance	PRα/LBD⁺	ACA	Age	FLT3 mutation
14	134	0	Y208N†	None	1§	ITD⁺
32	175	0	R217H†	NA	4§	ITD⁺
39	218	107	R217H†	NA	11§	—
5	265	118	N	t(3;11)‡	11§	—
10	265	130	N	add(22p)‡ add(7q)‡	3§	D835⁺
22	309	179	Δ412–414	NA	44	—
30	339	196	I273F	NA	43	ITD⁺
9	359	231	G289E	add(6)(q21)‡	35	—
17	363	218	R276Q and L224P†	None	65	ITD⁺ and D835⁺‡
7	401	279	G289E	+8	42	ITD⁺
11	520	365	T285A	None	28	—
27	528	365	R276Q	NA	32	—
37	546	365	G289R	NA	15	—
15	644*	365	R272Q	t(4;5)‡	13§	—
4	655*	365	N	i(8)(q10)‡	31	—
20	657*	365	R276W	+8	64	—
12	678*	365	N	+8‡	31	—
8	682*	365	G289R	+8 and 3ACA‡	49	—
40	686*	365	S287W	NA	49	—
3	718*	365	N	t(10;11)	17	—
1	728*	0	S287L	t(4;5),del(20)‡	64	—
6	874*	365	Δ207–208†	t(3;12)‡	18	—
19	1057*	365	N	ider(17q)	36	—
31	1431*	365	K238E†	NA	32	—

— indicates not applicable.

Relapse Off-ATRA.

Zone III LBD mutations.

Newly detected at relapse.

Pediatric cases.