WBC counts (× 109/L) as indication for leukapheresis in hyperleukocytosis
| . | Symptomatic . | Asymptomatic . |
|---|---|---|
| AML | > 50 000 | > 100 000 |
| ALL | > 150 000 | > 300 000 |
| CML | > 150 000 | No |
| CLL | > 500 000 | No |
| APL | No | No |
| . | Symptomatic . | Asymptomatic . |
|---|---|---|
| AML | > 50 000 | > 100 000 |
| ALL | > 150 000 | > 300 000 |
| CML | > 150 000 | No |
| CLL | > 500 000 | No |
| APL | No | No |
In the presence of unequivocal retinal findings, leukapheresis may be performed for even lower WBC counts.
CML indicates chronic myeloid leukemia; and CLL, chronic lymphocytic leukemia.