Dose selection scheme for creation of α (RA) and γ (RG) resistant HL60 clones
| Iteration . | 1 . | 2 . | 3 . | 4 . | 5 . | 6 . | 7 . | 8 . | 9 . | 10 . | 11 . | 12 . | 13 . | 14 . | 15 . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HL60 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| RA, Gy | 0.9 | 0.9 | 1.3 | 1.3 | 1.3 | 1.3 | 1.7 | 1.7 | 1.9 | 2.0 | 2.0 | 2.2 | 2.2 | 2.2 | 2.4 |
| RG, Gy | 2.5 | 2.5 | 3.3 | 3.3 | 3.3 | 3.3 | 3.8 | 3.8 | 4.0 | 4.5 | 4.5 | 5 | 5.5 | 6 | 6.5 |
| Iteration . | 1 . | 2 . | 3 . | 4 . | 5 . | 6 . | 7 . | 8 . | 9 . | 10 . | 11 . | 12 . | 13 . | 14 . | 15 . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HL60 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| RA, Gy | 0.9 | 0.9 | 1.3 | 1.3 | 1.3 | 1.3 | 1.7 | 1.7 | 1.9 | 2.0 | 2.0 | 2.2 | 2.2 | 2.2 | 2.4 |
| RG, Gy | 2.5 | 2.5 | 3.3 | 3.3 | 3.3 | 3.3 | 3.8 | 3.8 | 4.0 | 4.5 | 4.5 | 5 | 5.5 | 6 | 6.5 |
— indicates not applicable.