IPSS-R prognostic risk category clinical outcomes
| . | No. of patients . | Very low . | Low . | Intermediate . | High . | Very high . |
|---|---|---|---|---|---|---|
| Patients, % | 7012 | 19 | 38 | 20 | 13 | 10 |
| Survival, all* | 8.8 | 5.3 | 3.0 | 1.6 | 0.8 | |
| (7.8-9.9) | (5.1-5.7) | (2.7-3.3) | (1.5-1.7) | (0.7-0.8) | ||
| Hazard ratio | 0.5 | 1.0 | 2.0 | 3.2 | 8.0 | |
| (95% CI) | (0.46-0.59) | (0.93-1.1) | (1.8-2.1) | (2.9-3.5) | (7.2-8.8) | |
| Patients, % | 6485 | 19 | 37 | 20 | 13 | 11 |
| AML/25%*† | NR | 10.8 | 3.2 | 1.4 | 0.73 | |
| (14.5-NR) | (9.2-NR) | (2.8-4.4) | (1.1-1.7) | (0.7-0.9) | ||
| Hazard ratio | 0.5 | 1.0 | 3.0 | 6.2 | 12.7 | |
| (95% CI) | (0.4-0.6) | (0.9-1.2) | (2.7-3.5) | (5.4-7.2) | (10.6-15.2) |
| . | No. of patients . | Very low . | Low . | Intermediate . | High . | Very high . |
|---|---|---|---|---|---|---|
| Patients, % | 7012 | 19 | 38 | 20 | 13 | 10 |
| Survival, all* | 8.8 | 5.3 | 3.0 | 1.6 | 0.8 | |
| (7.8-9.9) | (5.1-5.7) | (2.7-3.3) | (1.5-1.7) | (0.7-0.8) | ||
| Hazard ratio | 0.5 | 1.0 | 2.0 | 3.2 | 8.0 | |
| (95% CI) | (0.46-0.59) | (0.93-1.1) | (1.8-2.1) | (2.9-3.5) | (7.2-8.8) | |
| Patients, % | 6485 | 19 | 37 | 20 | 13 | 11 |
| AML/25%*† | NR | 10.8 | 3.2 | 1.4 | 0.73 | |
| (14.5-NR) | (9.2-NR) | (2.8-4.4) | (1.1-1.7) | (0.7-0.9) | ||
| Hazard ratio | 0.5 | 1.0 | 3.0 | 6.2 | 12.7 | |
| (95% CI) | (0.4-0.6) | (0.9-1.2) | (2.7-3.5) | (5.4-7.2) | (10.6-15.2) |