Table 1

Immunologic parameters by sex

Normal range*Males (n = 208), median (range)Females, (n = 265) median (range)Mann-Whitney test
Immunoglobulins, mg/dL     
    IgG 700-1 600 244 (6-630) 246 (0-594) 0.66 
    IgA 70-400 8 (0-221) 8 (0-495) 0.38 
    IgM 40-230 19 (0-247) 24 (0-400) 0.009 
Lymphocytes (%)     
    T cells (n = 338) 55-89 74 (0-94) 75 (0-97) 0.40 
    B cells (n = 396) 5-15 9 (0-38) 10 (0-53) 0.16 
    Isotype switched memory B cells (n = 208) 6.5-29.2 0.88 (0-21) 1.3 (0-23) 0.03 
    Absolute CD4 count (n = 140) 480-1 700 CU/MM 582 (96-1 661) 698 (130-2 383) 0.13 
    CD4/CD8 ratio (n = 262) 1-3 1.5 (0-8) 1.6 (0-9) 0.31 
Lymphocyte proliferative response (cpm)     
    Phytohemagglutinin (n = 160) 16 000-29 000 16 848 (183-40 165) 16 383 (370-39 870) 0.49 
    Concanavalin A (n = 191) 10 000-24 000 10 077 (66-34 600) 9 540 (56-34 300) 0.53 
    Pokeweed mitogen (n = 196) 5 000-13 000 2 665 (32-19 800) 4 284 (28-18 734) 0.36 
Normal range*Males (n = 208), median (range)Females, (n = 265) median (range)Mann-Whitney test
Immunoglobulins, mg/dL     
    IgG 700-1 600 244 (6-630) 246 (0-594) 0.66 
    IgA 70-400 8 (0-221) 8 (0-495) 0.38 
    IgM 40-230 19 (0-247) 24 (0-400) 0.009 
Lymphocytes (%)     
    T cells (n = 338) 55-89 74 (0-94) 75 (0-97) 0.40 
    B cells (n = 396) 5-15 9 (0-38) 10 (0-53) 0.16 
    Isotype switched memory B cells (n = 208) 6.5-29.2 0.88 (0-21) 1.3 (0-23) 0.03 
    Absolute CD4 count (n = 140) 480-1 700 CU/MM 582 (96-1 661) 698 (130-2 383) 0.13 
    CD4/CD8 ratio (n = 262) 1-3 1.5 (0-8) 1.6 (0-9) 0.31 
Lymphocyte proliferative response (cpm)     
    Phytohemagglutinin (n = 160) 16 000-29 000 16 848 (183-40 165) 16 383 (370-39 870) 0.49 
    Concanavalin A (n = 191) 10 000-24 000 10 077 (66-34 600) 9 540 (56-34 300) 0.53 
    Pokeweed mitogen (n = 196) 5 000-13 000 2 665 (32-19 800) 4 284 (28-18 734) 0.36 
*

Normal range listed is for adult patients.

Statistically significant (P < .05).

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