Multivariate Cox model by survivin level (BM samples)
| Variable . | Estimate . | Hazard ratio . | 95% CI for hazard ratio . | P . |
|---|---|---|---|---|
| For OS | ||||
| Age | 0.05 | 1.05 | (1.04, 1.06) | < .001 |
| Sex, male | −0.31 | 0.73 | (0.57, 0.95) | .019 |
| Log2 (WBC) | 0.12 | 1.13 | (1.06, 1.21) | < .001 |
| BM blast | 0.01 | 1.01 | (1.00, 1.01) | .008 |
| Cyto (intermediate) | 0.73 | 2.08 | (0.95, 4.55) | .068 |
| Cyto (unfavorable) | 1.22 | 3.38 | (1.56, 7.35) | .002 |
| Survivin | 0.20 | 1.23 | (1.05, 1.43) | .011 |
| For EFS | ||||
| Age | 0.04 | 1.04 | (1.03, 1.05) | < .001 |
| Sex, male | −0.32 | 0.73 | (0.57, 0.93) | .012 |
| Log2 (WBC) | 0.10 | 1.11 | (1.04, 1.18) | .001 |
| BM blast | 0.01 | 1.01 | (1.00, 1.01) | < .001 |
| Cyto (intermediate) | 0.63 | 1.87 | (0.96, 3.64) | .064 |
| Cyto (unfavorable) | 1.09 | 2.97 | (1.54, 5.74) | .001 |
| Survivin | 0.13 | 1.14 | (0.98, 1.32) | .082 |
| Variable . | Estimate . | Hazard ratio . | 95% CI for hazard ratio . | P . |
|---|---|---|---|---|
| For OS | ||||
| Age | 0.05 | 1.05 | (1.04, 1.06) | < .001 |
| Sex, male | −0.31 | 0.73 | (0.57, 0.95) | .019 |
| Log2 (WBC) | 0.12 | 1.13 | (1.06, 1.21) | < .001 |
| BM blast | 0.01 | 1.01 | (1.00, 1.01) | .008 |
| Cyto (intermediate) | 0.73 | 2.08 | (0.95, 4.55) | .068 |
| Cyto (unfavorable) | 1.22 | 3.38 | (1.56, 7.35) | .002 |
| Survivin | 0.20 | 1.23 | (1.05, 1.43) | .011 |
| For EFS | ||||
| Age | 0.04 | 1.04 | (1.03, 1.05) | < .001 |
| Sex, male | −0.32 | 0.73 | (0.57, 0.93) | .012 |
| Log2 (WBC) | 0.10 | 1.11 | (1.04, 1.18) | .001 |
| BM blast | 0.01 | 1.01 | (1.00, 1.01) | < .001 |
| Cyto (intermediate) | 0.63 | 1.87 | (0.96, 3.64) | .064 |
| Cyto (unfavorable) | 1.09 | 2.97 | (1.54, 5.74) | .001 |
| Survivin | 0.13 | 1.14 | (0.98, 1.32) | .082 |