Multivariate Cox model by survivin level
| Variable . | Estimate . | Hazard ratio . | 95% CI for hazard ratio . | P . |
|---|---|---|---|---|
| For OS | ||||
| Age | 0.04 | 1.04 | (1.04, 1.05) | < .001 |
| Sex, male | −0.20 | 0.82 | (0.66, 1.01) | .063 |
| Log2 (WBC) | 0.12 | 1.12 | (1.06, 1.19) | < .001 |
| BM blast | 0.005 | 1.005 | (1.00, 1.01) | .021 |
| Cyto (intermediate) | 0.85 | 2.34 | (1.18,4.65) | .015 |
| Cyto (unfavorable) | 1.38 | 3.97 | (2.01,7.84) | < .001 |
| Survivin | 0.16 | 1.17 | (1.03,1.33) | .016 |
| For EFS | ||||
| Age | 0.03 | 1.03 | (1.03, 1.04) | < .001 |
| Sex, male | −0.24 | 0.78 | (0.64, 0.96) | .021 |
| Log2 (WBC) | 0.09 | 1.10 | (1.04, 1.16) | .001 |
| BM blast | 0.01 | 1.01 | (1.00, 1.01) | .001 |
| Cyto (intermediate) | 0.70 | 2.02 | (1.13,3.59) | .017 |
| Cyto (unfavorable) | 1.19 | 3.30 | (1.86, 5.86) | < .001 |
| Survivin | 0.14 | 1.15 | (1.02,1.30) | .023 |
| Variable . | Estimate . | Hazard ratio . | 95% CI for hazard ratio . | P . |
|---|---|---|---|---|
| For OS | ||||
| Age | 0.04 | 1.04 | (1.04, 1.05) | < .001 |
| Sex, male | −0.20 | 0.82 | (0.66, 1.01) | .063 |
| Log2 (WBC) | 0.12 | 1.12 | (1.06, 1.19) | < .001 |
| BM blast | 0.005 | 1.005 | (1.00, 1.01) | .021 |
| Cyto (intermediate) | 0.85 | 2.34 | (1.18,4.65) | .015 |
| Cyto (unfavorable) | 1.38 | 3.97 | (2.01,7.84) | < .001 |
| Survivin | 0.16 | 1.17 | (1.03,1.33) | .016 |
| For EFS | ||||
| Age | 0.03 | 1.03 | (1.03, 1.04) | < .001 |
| Sex, male | −0.24 | 0.78 | (0.64, 0.96) | .021 |
| Log2 (WBC) | 0.09 | 1.10 | (1.04, 1.16) | .001 |
| BM blast | 0.01 | 1.01 | (1.00, 1.01) | .001 |
| Cyto (intermediate) | 0.70 | 2.02 | (1.13,3.59) | .017 |
| Cyto (unfavorable) | 1.19 | 3.30 | (1.86, 5.86) | < .001 |
| Survivin | 0.14 | 1.15 | (1.02,1.30) | .023 |
CI indicates confidence interval; OS, overall survival; and EFS, event-free survival.