E-cadherin surface expression on subsets of mouse peripheral blood monocytes, DCs, and macrophages
| . | Steady state . | Inflammation . | Reference . |
|---|---|---|---|
| Peripheral blood monocyte subsets | |||
| CD115+Gr-1+ monocytes | (+) on 50% of population | (+) on whole population (colitis) | 81 |
| CD115+Gr-1− monocytes | (+/−) on 15% of population | (+/−) on whole population (colitis) | 81 |
| DC subsets | |||
| In vitro generated BM-DCs | (+) | 36 | |
| Tissues | |||
| LCs | (++) | (+/−) | 70 |
| Alveolar lung DCs | (−) | (+) (allergic asthma), (−) (pneumonitis) | 90 |
| Colon DCs | (+) on 3%-4% of CD11chi population | (+) on 70%-80% of CD11chi population (monocyte-derived DC during colitis) | 81 |
| Lymphoid organs | |||
| Splenic DCs | (+) on 3%-5% of CD11chi population | (+) on 10%-20% of CD11chi population (monocyte-derived DC during colitis) | 81 |
| Mesenteric LN DCs | (+) on 4%-6% of CD11chi population (CD11chi MHC IIhi CD103+ CD11bhet CD8αhet) | (+) on 40%-50% of CD11chi population (monocyte-derived DC during colitis) | 81 |
| Axillary LN DCs | (+) on 5%-7% of CD11chi population | ND | 81 |
| Macrophage subsets | |||
| Tissues | |||
| Peritoneal macrophages | (−) | (+) (T crassiceps helminth infection) | 90 |
| Alveolar lung macrophages | (−) | (+) (allergic asthma) (−) (pneumonitis) | 90 |
| Osteoclasts | (+) | 103 | |
| . | Steady state . | Inflammation . | Reference . |
|---|---|---|---|
| Peripheral blood monocyte subsets | |||
| CD115+Gr-1+ monocytes | (+) on 50% of population | (+) on whole population (colitis) | 81 |
| CD115+Gr-1− monocytes | (+/−) on 15% of population | (+/−) on whole population (colitis) | 81 |
| DC subsets | |||
| In vitro generated BM-DCs | (+) | 36 | |
| Tissues | |||
| LCs | (++) | (+/−) | 70 |
| Alveolar lung DCs | (−) | (+) (allergic asthma), (−) (pneumonitis) | 90 |
| Colon DCs | (+) on 3%-4% of CD11chi population | (+) on 70%-80% of CD11chi population (monocyte-derived DC during colitis) | 81 |
| Lymphoid organs | |||
| Splenic DCs | (+) on 3%-5% of CD11chi population | (+) on 10%-20% of CD11chi population (monocyte-derived DC during colitis) | 81 |
| Mesenteric LN DCs | (+) on 4%-6% of CD11chi population (CD11chi MHC IIhi CD103+ CD11bhet CD8αhet) | (+) on 40%-50% of CD11chi population (monocyte-derived DC during colitis) | 81 |
| Axillary LN DCs | (+) on 5%-7% of CD11chi population | ND | 81 |
| Macrophage subsets | |||
| Tissues | |||
| Peritoneal macrophages | (−) | (+) (T crassiceps helminth infection) | 90 |
| Alveolar lung macrophages | (−) | (+) (allergic asthma) (−) (pneumonitis) | 90 |
| Osteoclasts | (+) | 103 | |
A systematic analysis on all DC and macrophage subsets in vivo is lacking thus far.
hi indicates high; and het, heterogeneous.