Table 3

Characteristics of patients who experienced grade 3/4 thromboembolic events during prophylaxis

PatientCharacteristics at multiple myeloma diagnosis
Characteristics at VTE onset
Type of prophylaxisAge, ySexISS stageKPS scoreRisk factorsVTEOnset after enrollment, moTreatment
ASA 57 Male II 70 rHuEpo PE 1.57 Rd 
ASA 55 Female III 70 rHuEpo PE 0.63 Rd 
LMWH 58 Female III 80 None DVT 1.93 Rd 
ASA 57 Female 70 rHuEpo PE 0.87 Rd 
ASA 61 Female III 90 None DVT 1.03 Rd 
LMWH 52 Male 100 None DVT 2.33 Rd 
LMWH 56 Male 100 None DVT 9.8 MPR 
PatientCharacteristics at multiple myeloma diagnosis
Characteristics at VTE onset
Type of prophylaxisAge, ySexISS stageKPS scoreRisk factorsVTEOnset after enrollment, moTreatment
ASA 57 Male II 70 rHuEpo PE 1.57 Rd 
ASA 55 Female III 70 rHuEpo PE 0.63 Rd 
LMWH 58 Female III 80 None DVT 1.93 Rd 
ASA 57 Female 70 rHuEpo PE 0.87 Rd 
ASA 61 Female III 90 None DVT 1.03 Rd 
LMWH 52 Male 100 None DVT 2.33 Rd 
LMWH 56 Male 100 None DVT 9.8 MPR 

VTE indicates venous thromboembolism; ISS, International Staging System; KPS, Karnofsky performance status; ASA, aspirin; rHuEpo, recombinant human erythropoietin; PE, pulmonary embolism; Rd, lenalidomide and low-dose dexamethasone; LMWH, low-molecular-weight heparin; DVT, deep vein thrombosis; and MPR, melphalan, prednisone plus lenalidomide.

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