Table 1 Patient characteristics Patient... | American Society of Hematology

Table 1

Patient characteristics

Patient no.	Age, y	Nationality	Clinical features	Hematology	Chromosome fragility	Sensitivity to MMC	G₂/M block	Reference
MD1	11	United States	Visual impairment, hypotonia, areflexia, absent language, epilepsy, microsomy, and microcephaly	Normal	Negative	Mild	Mild	13
MD2	6	France	Hypotonia, severe developmental delay; rod–cone dystrophy, epilepsy, and autistic features	Normal	Negative	Mild	Mild	12
MD3	1	France	Severe developmental delay, visual impairment, microsomy, and microcephaly	Normal	Negative	ND	ND	Present study
MD4	3	France	Severe developmental delay, absent language, visual impairment, microsomy, and microcephaly	Normal	Negative	ND	ND	Present study

Patient no.	Age, y	Nationality	Clinical features	Hematology	Chromosome fragility	Sensitivity to MMC	G₂/M block	Reference
MD1	11	United States	Visual impairment, hypotonia, areflexia, absent language, epilepsy, microsomy, and microcephaly	Normal	Negative	Mild	Mild	13
MD2	6	France	Hypotonia, severe developmental delay; rod–cone dystrophy, epilepsy, and autistic features	Normal	Negative	Mild	Mild	12
MD3	1	France	Severe developmental delay, visual impairment, microsomy, and microcephaly	Normal	Negative	ND	ND	Present study
MD4	3	France	Severe developmental delay, absent language, visual impairment, microsomy, and microcephaly	Normal	Negative	ND	ND	Present study

MMC indicates mitomycin C; and MD, microdeletion.