Table 1

Prognostic impact of features associated with age in a univariate analysis and after adjustment for age

MarkerUnivariate result
With adjustment for age
Relative riskPRelative riskP
ABC GE 2.76 1.6 × 10-7 2.14 .00013 
BCL2 IHC 2.61 .00048 2.36 .0019 
IRF4 break 0.18 .09 0.33 .28 
1q21+ 1.44 .11 1.20 .44 
18q21+ 1.45 .06 1.23 .29 
7p22+ 1.63 .02 1.50 .05 
7q21+ 1.43 .09 1.28 .25 
3q aberration 1.43 .05 1.19 .34 
Genetic complexity* 1.08 .009 1.05 .12 
MarkerUnivariate result
With adjustment for age
Relative riskPRelative riskP
ABC GE 2.76 1.6 × 10-7 2.14 .00013 
BCL2 IHC 2.61 .00048 2.36 .0019 
IRF4 break 0.18 .09 0.33 .28 
1q21+ 1.44 .11 1.20 .44 
18q21+ 1.45 .06 1.23 .29 
7p22+ 1.63 .02 1.50 .05 
7q21+ 1.43 .09 1.28 .25 
3q aberration 1.43 .05 1.19 .34 
Genetic complexity* 1.08 .009 1.05 .12 

GE indicates gene expression; and IHC, immunohostochemistry.

*

Genetic complexity as a continuous variable.

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