Table 5 Factors associated with... | American Society of Hematology

Table 5

Factors associated with achievement of CR in patients treated with curative intent using VEPEMB, ABVD, and CLVPP (157)

Factor	No. of patients	Parameter	P
Age	157	Comparison of age (60-69 y vs 70-79 y vs > 80 y)	.32
Sex	157	Male vs female	.85
Stage	157	1 vs 2 vs 3 vs 4	.15
B symptoms	157	Present vs absent	.89
Histologic type	152	MC vs NS vs LRCHL vs unclassified	.27
No. of nodal sites	117	1-2 vs 3-4 vs > 4	.55
Serum LDH	129	Normal vs abnormal	.33
Lymphocyte count	154	< 1 vs 1-2 vs > 2 × 10⁹/L	.40
Hemoglobin	156	6-7.9 vs 8-9.9 vs 10-11.9 vs > 12 g/dL	.04
ADL	144	Maximum score 6 vs < 6	.001
Comorbidity score (modified ACE-27)	155	Frail vs nonfrail	CR, .01
			OS, .001
IDL	143	Score 0-2 vs 3-5 vs 6 vs 7-8	.01
ECOG	145	0-1 vs 2-3	.02
Bulk disease	145	Yes vs no	.23
Hasenclever Index	106	Low vs intermediate vs high	.06
Serum albumin	148	Normal vs abnormal	.02
EBV antigen Reed-Sternberg cells(available on VEPEMB patients only)	94	Positive vs negative	.71

Factor	No. of patients	Parameter	P
Age	157	Comparison of age (60-69 y vs 70-79 y vs > 80 y)	.32
Sex	157	Male vs female	.85
Stage	157	1 vs 2 vs 3 vs 4	.15
B symptoms	157	Present vs absent	.89
Histologic type	152	MC vs NS vs LRCHL vs unclassified	.27
No. of nodal sites	117	1-2 vs 3-4 vs > 4	.55
Serum LDH	129	Normal vs abnormal	.33
Lymphocyte count	154	< 1 vs 1-2 vs > 2 × 10⁹/L	.40
Hemoglobin	156	6-7.9 vs 8-9.9 vs 10-11.9 vs > 12 g/dL	.04
ADL	144	Maximum score 6 vs < 6	.001
Comorbidity score (modified ACE-27)	155	Frail vs nonfrail	CR, .01
			OS, .001
IDL	143	Score 0-2 vs 3-5 vs 6 vs 7-8	.01
ECOG	145	0-1 vs 2-3	.02
Bulk disease	145	Yes vs no	.23
Hasenclever Index	106	Low vs intermediate vs high	.06
Serum albumin	148	Normal vs abnormal	.02
EBV antigen Reed-Sternberg cells(available on VEPEMB patients only)	94	Positive vs negative	.71

MC indicates mixed cellularity; NS, nodular sclerosis; LRCHL, lymphocyte-rich classic HL; and LDH, lactate dehydrogenase.