Table 3 End points in longitudinal... | American Society of Hematology

Table 3

End points in longitudinal analyses

Events	PFS	FFS	EFS	OS	ATFS
No responses, or insufficient response to study therapy, after a predefined period of time*		Yes	Yes
Loss of responses to study treatment		Yes	Yes
Progression (AP/BC)	Yes	Yes	Yes
Adverse events leading to permanent discontinuation of study therapy (any grade)			Yes
Treatment change†					Yes
Deaths	Yes	Yes	Yes	Yes	Yes

Events	PFS	FFS	EFS	OS	ATFS
No responses, or insufficient response to study therapy, after a predefined period of time*		Yes	Yes
Loss of responses to study treatment		Yes	Yes
Progression (AP/BC)	Yes	Yes	Yes
Adverse events leading to permanent discontinuation of study therapy (any grade)			Yes
Treatment change†					Yes
Deaths	Yes	Yes	Yes	Yes	Yes

Time point of assessment are defined in Table 1.

Discontinuation of treatment for patients in molecular response is not considered as a “treatment change” in this analysis.