Table 1

Immunogenic peptides on cyclin-A1 isoform c

AA positionAA sequenceDonorHLA restrictionClone available
118-127 YEVDTGTLKS 2264 B*4001 Yes 
120-131 VDTGTLKSDLHF 2196 B*5701 Yes 
167-175 YAEEIYQYL 2264 B*4001 Yes 
218-226 AETLYLAVN 2196 A*0201 No 
227-235 FLDRFLSCM 2196 A*0201 Yes 
253-261 ASKYEEIYP 2196 ND No 
330-339 LEADPFLKYL 2264 B*4001 No 
341-351 SLIAAAAFCLA 2264 A*0201 Yes 
AA positionAA sequenceDonorHLA restrictionClone available
118-127 YEVDTGTLKS 2264 B*4001 Yes 
120-131 VDTGTLKSDLHF 2196 B*5701 Yes 
167-175 YAEEIYQYL 2264 B*4001 Yes 
218-226 AETLYLAVN 2196 A*0201 No 
227-235 FLDRFLSCM 2196 A*0201 Yes 
253-261 ASKYEEIYP 2196 ND No 
330-339 LEADPFLKYL 2264 B*4001 No 
341-351 SLIAAAAFCLA 2264 A*0201 Yes 

The HLA restriction of the HLA B epitopes was determined using ICS for IFN-γ production with 721.221 stimulator cells transfected with a single HLA allele or allogeneic LCLs sharing one or 2 HLA class I alleles with the respective donor.

ND indicates not determined.

Close Modal

or Create an Account

Close Modal
Close Modal