Immunologic analysis of patients 1 and 2
| . | Patient 1 . | Patient 2 (treated with IVIG) . | |
|---|---|---|---|
| Age at analysis, mo | 9 | 9 | 20 |
| Serum immunoglobulin levels, g/L (control) | |||
| IgG | 10.63 (4.51-10.46) | 8.44 (4.51-10.46) | 10.37 (7.15-9.07) |
| IgA | 1.36 (0.14-0.64) | 1.88 (0.14-0.64) | 3.93 (0.22-1.44) |
| IgM | 0.4 (0.33-1.00) | 0.17 (0.33-1.00) | 0.20 (0.34-1.28) |
| Age at analysis | 2 y | 2 mo | 23 mo |
| T-cell proliferation, SI (control) | 9.3 (206.9 ± 142.5) | 55.3 (64.8 ± 8.1) | 7.2 (89.4 ± 31.2) |
| . | Patient 1 . | Patient 2 (treated with IVIG) . | |
|---|---|---|---|
| Age at analysis, mo | 9 | 9 | 20 |
| Serum immunoglobulin levels, g/L (control) | |||
| IgG | 10.63 (4.51-10.46) | 8.44 (4.51-10.46) | 10.37 (7.15-9.07) |
| IgA | 1.36 (0.14-0.64) | 1.88 (0.14-0.64) | 3.93 (0.22-1.44) |
| IgM | 0.4 (0.33-1.00) | 0.17 (0.33-1.00) | 0.20 (0.34-1.28) |
| Age at analysis | 2 y | 2 mo | 23 mo |
| T-cell proliferation, SI (control) | 9.3 (206.9 ± 142.5) | 55.3 (64.8 ± 8.1) | 7.2 (89.4 ± 31.2) |
Control values of serum immunoglobulin levels are based on children aged either 7 to 9 months or 1 to 2 years and are shown as the mean ± SD. The T-cell proliferation assay was performed as described previously17 with at least three healthy adults as controls.
SI indicates stimulation index; and IVIG, 2.5 g of monthly IV immune globulin infusion.