Surface marker analysis of peripheral mononuclear cells of patients 1 and 2
| . | Patient 1 . | Patient 2 . | Healthy controls . | |
|---|---|---|---|---|
| Age at analysis | 2 y | 2 mo | 19 mo | |
| CD3 | 1503 | 2366 | 1014 | 2997 ± 1751 |
| CD4 | 292 | 1583 | 374 | 1683 ± 874 |
| CD8 | 1160 | 783 | 547 | 1114 ± 976 |
| TCRαβ | 1386 | 2295 | 439 | 2620 ± 1612 |
| TCRγδ | 109 | 74 | 574 | 343 ± 177 |
| CD4+CD45RA | 58 | 1336 | 105 | 1471 ± 890 |
| CD4+CD45RO | 263 | 307 | 266 | 497 ± 189 |
| CD8+CD45RA | 1178 | 783 | 297 | 1083 ± 1078 |
| CD8+CD45RO | 361 | 21 | 250 | 385 ± 442 |
| CD4+CD25 | 80 | 427 | 93 | 210 ± 99 |
| CD19 | 1200 | 941 | 1543 | 1252 ± 1145 |
| CD20 | 1189 | 931 | 1536 | 1125 ± 837 |
| CD19+Sm-IgG | 7 | 18 | 17 | 54 ± 21 |
| CD19+Sm-IgA | 15 | 4 | 14 | 18 ± 14 |
| CD19+Sm-IgM | 1171 | 910 | 1505 | 1057 ± 881 |
| CD19+Sm-IgD | 1171 | 906 | 1495 | 1052 ± 884 |
| CD16 | 912 | 176 | 24 | 287 ± 200 |
| CD56 | 908 | 176 | 24 | 306 ± 207 |
| . | Patient 1 . | Patient 2 . | Healthy controls . | |
|---|---|---|---|---|
| Age at analysis | 2 y | 2 mo | 19 mo | |
| CD3 | 1503 | 2366 | 1014 | 2997 ± 1751 |
| CD4 | 292 | 1583 | 374 | 1683 ± 874 |
| CD8 | 1160 | 783 | 547 | 1114 ± 976 |
| TCRαβ | 1386 | 2295 | 439 | 2620 ± 1612 |
| TCRγδ | 109 | 74 | 574 | 343 ± 177 |
| CD4+CD45RA | 58 | 1336 | 105 | 1471 ± 890 |
| CD4+CD45RO | 263 | 307 | 266 | 497 ± 189 |
| CD8+CD45RA | 1178 | 783 | 297 | 1083 ± 1078 |
| CD8+CD45RO | 361 | 21 | 250 | 385 ± 442 |
| CD4+CD25 | 80 | 427 | 93 | 210 ± 99 |
| CD19 | 1200 | 941 | 1543 | 1252 ± 1145 |
| CD20 | 1189 | 931 | 1536 | 1125 ± 837 |
| CD19+Sm-IgG | 7 | 18 | 17 | 54 ± 21 |
| CD19+Sm-IgA | 15 | 4 | 14 | 18 ± 14 |
| CD19+Sm-IgM | 1171 | 910 | 1505 | 1057 ± 881 |
| CD19+Sm-IgD | 1171 | 906 | 1495 | 1052 ± 884 |
| CD16 | 912 | 176 | 24 | 287 ± 200 |
| CD56 | 908 | 176 | 24 | 306 ± 207 |
Surface markers expressed by XL-EDA-ID patients' PBMCs are shown as absolute counts per microliter of peripheral blood. Healthy control values are based on children aged 1 to 6 years and are shown as the mean ± SD.
Sm indicates the surface membrane.