Characteristics of cardiac responders
| Characteristic . | Patient 1-384 . | Patient 2-709 . | Patient 3-559 . | Patient 4-838 . |
|---|---|---|---|---|
| NT-proBNP, ng/L | 3507/4607 | 389/357 | 7351/7295 | 122/148 |
| Troponin T, μg/L | 0.01/0.02 | 0.01/0.01 | 0.12/0.11 | 0.01/0.01 |
| IVS, mm | 12/10 | 15/12 | 20/13 | 15/11 |
| Ejection fraction, % | 49/53 | 66/68 | 53/44 | 68/70 |
| NYHA class | 1/1 | 1/1 | 2/1 | 1/1 |
| Time to organ response, mo | 3 | 6 | 18 | 6 |
| Best hematologic response | PR | PR | VGPR | PR |
| Vital status | Dead at 19.3 mo | Alive at 33.4 mo | Dead at 21.1 mo | Alive at 31 mo |
| Progression status | Progression at 14.5 mo | Progression-free at 1 mo | Progression-free at 20.5 mo | Progression at 21 mo |
| Characteristic . | Patient 1-384 . | Patient 2-709 . | Patient 3-559 . | Patient 4-838 . |
|---|---|---|---|---|
| NT-proBNP, ng/L | 3507/4607 | 389/357 | 7351/7295 | 122/148 |
| Troponin T, μg/L | 0.01/0.02 | 0.01/0.01 | 0.12/0.11 | 0.01/0.01 |
| IVS, mm | 12/10 | 15/12 | 20/13 | 15/11 |
| Ejection fraction, % | 49/53 | 66/68 | 53/44 | 68/70 |
| NYHA class | 1/1 | 1/1 | 2/1 | 1/1 |
| Time to organ response, mo | 3 | 6 | 18 | 6 |
| Best hematologic response | PR | PR | VGPR | PR |
| Vital status | Dead at 19.3 mo | Alive at 33.4 mo | Dead at 21.1 mo | Alive at 31 mo |
| Progression status | Progression at 14.5 mo | Progression-free at 1 mo | Progression-free at 20.5 mo | Progression at 21 mo |
All results except for last 4 rows are reported as baseline value/value at “cardiac response.”