Table 2

Patient outcomes (N = 33)

Confirmed response rate 48% (95% CI, 30-66) 
    Complete response 1 (3%) 
    Very good partial response 5 (15%) 
    Partial response 10 (30%) 
    Stable disease 11 (33%) 
    Not available* 2 (6%) 
Organ response 5 (15%) 
    Heart involvement 27 
    Response 4 (15%) 
    Kidney involvement 12 
    Response 2 (17%) 
    Liver involvement 
    Response 
Median time to hematologic response (PR+) 1.9 mo (range: 0.9-11.3) 
Median duration of response 19 mo (95% CI: 8.3-NA) 
Median overall survival 27.9 mo (95% CI: 14.6-NA) 
    12 mo 76% (95% CI: 62-92) 
Median progression-free survival 14.1 (95% CI: 9.7-21.1) 
    12 mo 59% (95% CI: 44-79) 
Confirmed response rate 48% (95% CI, 30-66) 
    Complete response 1 (3%) 
    Very good partial response 5 (15%) 
    Partial response 10 (30%) 
    Stable disease 11 (33%) 
    Not available* 2 (6%) 
Organ response 5 (15%) 
    Heart involvement 27 
    Response 4 (15%) 
    Kidney involvement 12 
    Response 2 (17%) 
    Liver involvement 
    Response 
Median time to hematologic response (PR+) 1.9 mo (range: 0.9-11.3) 
Median duration of response 19 mo (95% CI: 8.3-NA) 
Median overall survival 27.9 mo (95% CI: 14.6-NA) 
    12 mo 76% (95% CI: 62-92) 
Median progression-free survival 14.1 (95% CI: 9.7-21.1) 
    12 mo 59% (95% CI: 44-79) 
*

Patients went off treatment before first evaluation (death, n = 1; refusal, n = 1).

By Kaplan-Meier.

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