Treatment history, organ involvement, transplant candidacy, response to CyBorD therapy, and receipt of BMT for 17 patients with AL
| Patient no. . | Treatment history . | Organ involvement* . | Transplant candidacy . | Hematologic response . | Received autologous BMT? . |
|---|---|---|---|---|---|
| 1 | Naive | R | No | CR | NA |
| 2 | Naive | C, P | No | CR | NA |
| 3 | Naive | R, H, G | No | CR | NA |
| 4 | Naive | R, C, S | No | CR | Yes |
| 5 | Naive | R | No | PR | Yes |
| 6 | Naive | R | Yes | PR | Yes |
| 7 | Naive | R, S | Yes | CR | Yes |
| 8 | Naive | R, C, G, N | Yes | No response | Yes |
| 9 | Naive | R, C | No | CR | NA |
| 10 | Naive | R, C, G | No | PR | NA |
| 11 | TD (> 10 cycles); low dose MD (3 cycles) | R, C, H | No | PR | NA |
| 12 | MD (7 cycles); CRD (3 cycles) | R, C | No | CR | NA |
| 13 | MD (7 cycles) | C, G | No | CR | NA |
| 14 | CRD (6 cycles) | R, C, H, G | No | CR | NA |
| 15 | DVD (6 cycles) | R, H | No | CR | NA |
| 16 | RD (1 year) | P, S | Yes | CR | No (failed harvest) |
| 17 | RD (1 cycle) | R, C | No | CR | Eligible |
| Patient no. . | Treatment history . | Organ involvement* . | Transplant candidacy . | Hematologic response . | Received autologous BMT? . |
|---|---|---|---|---|---|
| 1 | Naive | R | No | CR | NA |
| 2 | Naive | C, P | No | CR | NA |
| 3 | Naive | R, H, G | No | CR | NA |
| 4 | Naive | R, C, S | No | CR | Yes |
| 5 | Naive | R | No | PR | Yes |
| 6 | Naive | R | Yes | PR | Yes |
| 7 | Naive | R, S | Yes | CR | Yes |
| 8 | Naive | R, C, G, N | Yes | No response | Yes |
| 9 | Naive | R, C | No | CR | NA |
| 10 | Naive | R, C, G | No | PR | NA |
| 11 | TD (> 10 cycles); low dose MD (3 cycles) | R, C, H | No | PR | NA |
| 12 | MD (7 cycles); CRD (3 cycles) | R, C | No | CR | NA |
| 13 | MD (7 cycles) | C, G | No | CR | NA |
| 14 | CRD (6 cycles) | R, C, H, G | No | CR | NA |
| 15 | DVD (6 cycles) | R, H | No | CR | NA |
| 16 | RD (1 year) | P, S | Yes | CR | No (failed harvest) |
| 17 | RD (1 cycle) | R, C | No | CR | Eligible |
BMT indicates bone marrow transplantation; TD, thalidomide and dexamethasone; MD, melphalan and dexamethasone; CRD, cyclophosphamide, revlimid, and dexamethasone; DVD, Doxil, vincristine, and dexamethasone; R, renal; C, cardiac; H, hepatic; G, gastrointestinal; P, pulmonary; N, nerves; S, soft tissues; and NA, not applicable.