Clinical and laboratory features among 48 patients with SWM
| . | Progression to WM (N = 34) . | Nonprogression (N = 12) . | Total (N = 48) . | Comments . |
|---|---|---|---|---|
| Male (%) | 65 | 83 | ||
| Age at diagnosis, y | ||||
| Median | 62 | 65 | 63 | Only 1 person < 40 y |
| Range | 39-87 | |||
| Liver palpable, N* | 4 | 1 | ||
| Spleen palpable, N* | 1 | 1 | ||
| Lymphadenopathy, N* | 4 | 0 | ||
| Hemoglobin, g/dL | ||||
| Median | 11.4 | 12.8 | 11.8 | < 10 g/dL in 8% |
| Range | 8.7-14.1 | 8.7-15.3 | 8.7-15.3 | < 12 g/dL in 54% |
| Serum monoclonal protein, g/dL | ||||
| Median | 3.4 | 3.0 | 3.3 | < 3 g dL in 25% |
| Range | 1.5-5.2 | 1.8-4.0 | 1.5-5.2 | ≥ 4 g/dL in 21% |
| Serum creatinine, mg/dL | ||||
| Median | 1.1 | 1.1 | 1.1 | > 2 mg/dL in 2% (missing in 2) |
| Range | .6-2.1 | .7-1.4 | .6-2.1 | |
| β2-microglobulin, μg/mL | ≤ 1.8 μg/mL in 4 | |||
| Median | 2.1 | 2.2 | 2.14 | ≥ 3 μg/mL in 3 (missing in 26) |
| Range | 1.6-4.0 | 1.5-3.2 | 1.5-4.0 | |
| Urine monoclonal protein, g/24 hours | < 0.1 g/24 h in 70% | |||
| Median | .1 | .05 | > 0.2 g/24 h in 17% | |
| Range | Not measurable to 1.4 | Not measurable to 0.3 | Not measurable to 1.4 | > 1.0 g/24 h in 3% (missing in 18) |
| Bone marrow lymphoplasmacytic cells, % | ||||
| Median | 40 | 15 | 30 | ≥ 10% in 94% |
| Range | 8-80 | 3-30 | 3-80 | ≥ 50% in 27% |
| . | Progression to WM (N = 34) . | Nonprogression (N = 12) . | Total (N = 48) . | Comments . |
|---|---|---|---|---|
| Male (%) | 65 | 83 | ||
| Age at diagnosis, y | ||||
| Median | 62 | 65 | 63 | Only 1 person < 40 y |
| Range | 39-87 | |||
| Liver palpable, N* | 4 | 1 | ||
| Spleen palpable, N* | 1 | 1 | ||
| Lymphadenopathy, N* | 4 | 0 | ||
| Hemoglobin, g/dL | ||||
| Median | 11.4 | 12.8 | 11.8 | < 10 g/dL in 8% |
| Range | 8.7-14.1 | 8.7-15.3 | 8.7-15.3 | < 12 g/dL in 54% |
| Serum monoclonal protein, g/dL | ||||
| Median | 3.4 | 3.0 | 3.3 | < 3 g dL in 25% |
| Range | 1.5-5.2 | 1.8-4.0 | 1.5-5.2 | ≥ 4 g/dL in 21% |
| Serum creatinine, mg/dL | ||||
| Median | 1.1 | 1.1 | 1.1 | > 2 mg/dL in 2% (missing in 2) |
| Range | .6-2.1 | .7-1.4 | .6-2.1 | |
| β2-microglobulin, μg/mL | ≤ 1.8 μg/mL in 4 | |||
| Median | 2.1 | 2.2 | 2.14 | ≥ 3 μg/mL in 3 (missing in 26) |
| Range | 1.6-4.0 | 1.5-3.2 | 1.5-4.0 | |
| Urine monoclonal protein, g/24 hours | < 0.1 g/24 h in 70% | |||
| Median | .1 | .05 | > 0.2 g/24 h in 17% | |
| Range | Not measurable to 1.4 | Not measurable to 0.3 | Not measurable to 1.4 | > 1.0 g/24 h in 3% (missing in 18) |
| Bone marrow lymphoplasmacytic cells, % | ||||
| Median | 40 | 15 | 30 | ≥ 10% in 94% |
| Range | 8-80 | 3-30 | 3-80 | ≥ 50% in 27% |
Information not available on 7 patients.