SNPs positively associated with MPV
| SNP . | Alleles . | β . | 95% CI . | P . | |
|---|---|---|---|---|---|
| Females (n = 2042) | |||||
| rs342293 | C/G vs C/C | 0.134 | 0.0441 to 0.224 | .0035 | |
| G/G vs C/C | 0.295 | 0.182 to 0.408 | <.0001 | ||
| rs7961894 | C/T vs C/C | 0.218 | 0.121 to 0.316 | <.0001 | |
| T/T vs C/C | 0.968 | 0.559 to 1.38 | <.0001 | ||
| rs12485738 | G/A vs G/G | 0.101 | 0.0157 to 0.186 | .020 | |
| A/A vs G/G | 0.320 | 0.197 to 0.443 | <.0001 | ||
| rs649729 | A/T vs A/A | 0.152 | 0.0692 to 0.234 | .00032 | |
| T/T vs A/A | 0.172 | 0.0244 to 0.319 | .022 | ||
| rs342251 | G/A vs G/G | 0.134 | 0.0454 to 0.223 | .0031 | |
| A/A vs G/G | 0.250 | 0.135 to 0.365 | <.0001 | ||
| rs17568628 | T/C vs T/T | 0.345 | 0.182 to 0.509 | <.0001 | |
| C/C vs T/T | 0.625 | –1.16 to 2.41 | .49 | ||
| rs4774471 | T/A vs T/T | 0.0861 | 0.00249 to 0.170 | .044 | |
| A/A vs T/T | 0.278 | 0.146 to 0.411 | <.0001 | ||
| Males (n = 2131) | |||||
| rs342293 | C/G vs C/C | 0.0286 | –0.0593 to 0.117 | .52 | |
| G/G vs C/C | 0.229 | 0.121 to 0.338 | <.0001 | ||
| rs7961894 | C/T vs C/C | 0.253 | 0.155 to 0.351 | <.0001 | |
| T/T vs C/C | 0.475 | 0.147 to 0.802 | .0045 | ||
| rs10876550 | A/G vs A/A | 0.121 | 0.0326 to 0.209 | .0073 | |
| G/G vs A/A | 0.205 | 0.0957 to 0.314 | .00024 | ||
| rs342251 | G/A vs G/G | 0.0319 | –0.0547 to 0.118 | .47 | |
| A/A vs G/G | 0.243 | 0.133 to 0.353 | <.0001 | ||
| SNP . | Alleles . | β . | 95% CI . | P . | |
|---|---|---|---|---|---|
| Females (n = 2042) | |||||
| rs342293 | C/G vs C/C | 0.134 | 0.0441 to 0.224 | .0035 | |
| G/G vs C/C | 0.295 | 0.182 to 0.408 | <.0001 | ||
| rs7961894 | C/T vs C/C | 0.218 | 0.121 to 0.316 | <.0001 | |
| T/T vs C/C | 0.968 | 0.559 to 1.38 | <.0001 | ||
| rs12485738 | G/A vs G/G | 0.101 | 0.0157 to 0.186 | .020 | |
| A/A vs G/G | 0.320 | 0.197 to 0.443 | <.0001 | ||
| rs649729 | A/T vs A/A | 0.152 | 0.0692 to 0.234 | .00032 | |
| T/T vs A/A | 0.172 | 0.0244 to 0.319 | .022 | ||
| rs342251 | G/A vs G/G | 0.134 | 0.0454 to 0.223 | .0031 | |
| A/A vs G/G | 0.250 | 0.135 to 0.365 | <.0001 | ||
| rs17568628 | T/C vs T/T | 0.345 | 0.182 to 0.509 | <.0001 | |
| C/C vs T/T | 0.625 | –1.16 to 2.41 | .49 | ||
| rs4774471 | T/A vs T/T | 0.0861 | 0.00249 to 0.170 | .044 | |
| A/A vs T/T | 0.278 | 0.146 to 0.411 | <.0001 | ||
| Males (n = 2131) | |||||
| rs342293 | C/G vs C/C | 0.0286 | –0.0593 to 0.117 | .52 | |
| G/G vs C/C | 0.229 | 0.121 to 0.338 | <.0001 | ||
| rs7961894 | C/T vs C/C | 0.253 | 0.155 to 0.351 | <.0001 | |
| T/T vs C/C | 0.475 | 0.147 to 0.802 | .0045 | ||
| rs10876550 | A/G vs A/A | 0.121 | 0.0326 to 0.209 | .0073 | |
| G/G vs A/A | 0.205 | 0.0957 to 0.314 | .00024 | ||
| rs342251 | G/A vs G/G | 0.0319 | –0.0547 to 0.118 | .47 | |
| A/A vs G/G | 0.243 | 0.133 to 0.353 | <.0001 | ||
Linear regression models for females and males adjusted for age. SNPs positively associated with MPV and shared by both males and females are shown in bold. Seventy-two tests were performed per sex (Bonferroni corrected α, .000694).