Sex-specific β estimates of determinants for MPV in the population sample
| . | Females (n = 7081) . | Males (n = 7386) . | ||||
|---|---|---|---|---|---|---|
| β . | 95% CI . | P . | β . | 95% CI . | P . | |
| Age (per 5 y) | 0.00776 | –0.00672 to 0.0222 | .29 | −0.00134 | –0.0120 to 0.00930 | .80 |
| Menopause (%) | −0.0595 | –0.126 to 0.00731 | .081 | — | — | |
| Menstruation (%) | 0.123 | 0.0232 to 0.224 | .016 | — | — | |
| HRT (%) | 0.0429 | –0.0224 to 0.108 | .20 | — | — | |
| Oral contraceptives (%) | 0.150 | 0.0649 to 0.236 | .00057 | — | — | |
| Hypertension (%) | 0.0351 | –0.0181 to 0.0883 | .20 | 0.0530 | 0.00520 to 0.101 | .030 |
| Smoking (%) | 0.0476 | –0.00686 to 0.102 | .087 | 0.179 | 0.129 to 0.230 | <.0001 |
| Dyslipidemia (%) | −0.0410 | –0.0925 to 0.0105 | .12 | 0.0224 | –0.0185 to 0.0632 | .28 |
| Diabetes (%) | 0.0591 | –0.0428 to 0.161 | .26 | 0.0358 | –0.0461 to 0.118 | .39 |
| Obesity (%) | 0.0273 | –0.0234 to 0.0780 | .29 | 0.0280 | –0.0181 to 0.0740 | .23 |
| Family history of MI or stroke (%) | −0.0161 | –0.0623 to 0.0300 | .49 | 0.0281 | –0.0197 to 0.0760 | .25 |
| Beta blockers (%) | 0.00560 | –0.0703 to 0.0815 | .89 | 0.0542 | –0.0166 to 0.125 | .13 |
| Antiplatelets (%) | 0.0150 | –0.132 to 0.161 | .84 | −0.0324 | –0.140 to 0.0755 | .56 |
| Antihypertensives (%) | −0.0298 | –0.123 to 0.0631 | .53 | −0.0655 | –0.160 to 0.0288 | .17 |
| Aspirin (%) | 0.0512 | –0.104 to 0.207 | .52 | 0.0819 | –0.0294 to 0.193 | .15 |
| Antilipemic drugs (%) | 0.0130 | –0.0606 to 0.0867 | .73 | 0.00998 | –0.0537 to 0.0737 | .76 |
| ACE inhibitors (%) | −0.0282 | –0.108 to 0.0518 | .49 | 0.0557 | –0.0268 to 0.138 | .19 |
| Diuretics (%) | 0.0487 | –0.0458 to 0.143 | .31 | 0.0703 | –0.0225 to 0.163 | .14 |
| WBC (× 109/L) | 0.0685 | 0.0574 to 0.0796 | <.0001 | 0.0394 | 0.0308 to 0.0479 | <.0001 |
| Platelets (× 109/L) | –0.00440 | –0.00469 to −0.00411 | <.0001 | –0.00456 | –0.00489 to −0.00424 | <.0001 |
| CRP (mg/L) | –0.00470 | –0.00910 to −0.000295 | .037 | –0.00494 | –0.00890 to −0.000981 | .014 |
| Fibrinogen (mg/dL) | 0.000652 | 0.000347 to 0.000956 | <.0001 | 0.000812 | 0.000511 to 0.00111 | <.0001 |
| Glucose (mg/dL) | 0.00126 | –0.000120 to 0.00263 | .074 | 0.00184 | 0.000642 to 0.00305 | .0027 |
| Hemoglobin (g/dL) | 0.00311 | –0.0176 to 0.0239 | .77 | −0.0100 | –0.0293 to 0.00926 | .31 |
| . | Females (n = 7081) . | Males (n = 7386) . | ||||
|---|---|---|---|---|---|---|
| β . | 95% CI . | P . | β . | 95% CI . | P . | |
| Age (per 5 y) | 0.00776 | –0.00672 to 0.0222 | .29 | −0.00134 | –0.0120 to 0.00930 | .80 |
| Menopause (%) | −0.0595 | –0.126 to 0.00731 | .081 | — | — | |
| Menstruation (%) | 0.123 | 0.0232 to 0.224 | .016 | — | — | |
| HRT (%) | 0.0429 | –0.0224 to 0.108 | .20 | — | — | |
| Oral contraceptives (%) | 0.150 | 0.0649 to 0.236 | .00057 | — | — | |
| Hypertension (%) | 0.0351 | –0.0181 to 0.0883 | .20 | 0.0530 | 0.00520 to 0.101 | .030 |
| Smoking (%) | 0.0476 | –0.00686 to 0.102 | .087 | 0.179 | 0.129 to 0.230 | <.0001 |
| Dyslipidemia (%) | −0.0410 | –0.0925 to 0.0105 | .12 | 0.0224 | –0.0185 to 0.0632 | .28 |
| Diabetes (%) | 0.0591 | –0.0428 to 0.161 | .26 | 0.0358 | –0.0461 to 0.118 | .39 |
| Obesity (%) | 0.0273 | –0.0234 to 0.0780 | .29 | 0.0280 | –0.0181 to 0.0740 | .23 |
| Family history of MI or stroke (%) | −0.0161 | –0.0623 to 0.0300 | .49 | 0.0281 | –0.0197 to 0.0760 | .25 |
| Beta blockers (%) | 0.00560 | –0.0703 to 0.0815 | .89 | 0.0542 | –0.0166 to 0.125 | .13 |
| Antiplatelets (%) | 0.0150 | –0.132 to 0.161 | .84 | −0.0324 | –0.140 to 0.0755 | .56 |
| Antihypertensives (%) | −0.0298 | –0.123 to 0.0631 | .53 | −0.0655 | –0.160 to 0.0288 | .17 |
| Aspirin (%) | 0.0512 | –0.104 to 0.207 | .52 | 0.0819 | –0.0294 to 0.193 | .15 |
| Antilipemic drugs (%) | 0.0130 | –0.0606 to 0.0867 | .73 | 0.00998 | –0.0537 to 0.0737 | .76 |
| ACE inhibitors (%) | −0.0282 | –0.108 to 0.0518 | .49 | 0.0557 | –0.0268 to 0.138 | .19 |
| Diuretics (%) | 0.0487 | –0.0458 to 0.143 | .31 | 0.0703 | –0.0225 to 0.163 | .14 |
| WBC (× 109/L) | 0.0685 | 0.0574 to 0.0796 | <.0001 | 0.0394 | 0.0308 to 0.0479 | <.0001 |
| Platelets (× 109/L) | –0.00440 | –0.00469 to −0.00411 | <.0001 | –0.00456 | –0.00489 to −0.00424 | <.0001 |
| CRP (mg/L) | –0.00470 | –0.00910 to −0.000295 | .037 | –0.00494 | –0.00890 to −0.000981 | .014 |
| Fibrinogen (mg/dL) | 0.000652 | 0.000347 to 0.000956 | <.0001 | 0.000812 | 0.000511 to 0.00111 | <.0001 |
| Glucose (mg/dL) | 0.00126 | –0.000120 to 0.00263 | .074 | 0.00184 | 0.000642 to 0.00305 | .0027 |
| Hemoglobin (g/dL) | 0.00311 | –0.0176 to 0.0239 | .77 | −0.0100 | –0.0293 to 0.00926 | .31 |
Multivariable linear regression model for MPV with adjustment for all variables included in the table. Males and females: R2, 0.119. P values <.05 are shown in bold.
ACE, angiotensin-converting enzyme; HRT, hormone replacement therapy.