Table 3

T-cell composition of gut biopsy samples

Patient groupMedian colonic CD4+ T-cells, % (range)Median colonic CD4+ T cells/g (range)Median colonic CD4/CD8 ratio (range)
Cases (n = 3) 59.6 (53.2-73.7) 4.45 × 106 (3.35 × 106-2.67 × 107) 1.97 (1.77-3.7) 
HIV-negative (n = 12) 57. 5 (42.9-70.8) 3.59 × 106 (4.53 × 105-6.23 × 106) 2.84 (1.14-4.99) 
LTNPs/ECs (n = 12) 54.7 (24.1-69) 2.74 × 106 (6.32 × 105-1.74 × 107) 2.23 (0.58-4.46) 
Progressors (n = 13) 5.8 (0.1-21.6)* 5.63 × 105 (1.13 × 104-4.75 × 106) 0.08 (0.002-0.32)* 
Rx<50 (n = 16) 36.6 (24.6-55.8)* 2.61 × 106 (9.39 × 105-1.33 × 107) 0.84 (0.47-2.32)* 
Patient groupMedian colonic CD4+ T-cells, % (range)Median colonic CD4+ T cells/g (range)Median colonic CD4/CD8 ratio (range)
Cases (n = 3) 59.6 (53.2-73.7) 4.45 × 106 (3.35 × 106-2.67 × 107) 1.97 (1.77-3.7) 
HIV-negative (n = 12) 57. 5 (42.9-70.8) 3.59 × 106 (4.53 × 105-6.23 × 106) 2.84 (1.14-4.99) 
LTNPs/ECs (n = 12) 54.7 (24.1-69) 2.74 × 106 (6.32 × 105-1.74 × 107) 2.23 (0.58-4.46) 
Progressors (n = 13) 5.8 (0.1-21.6)* 5.63 × 105 (1.13 × 104-4.75 × 106) 0.08 (0.002-0.32)* 
Rx<50 (n = 16) 36.6 (24.6-55.8)* 2.61 × 106 (9.39 × 105-1.33 × 107) 0.84 (0.47-2.32)* 
*

P < .05, cases versus other patient groups.

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