Table 1 Patient characteristics . Case 1... | American Society of Hematology

Table 1

Patient characteristics

	Case 1	Case 2	Case 3	Case 4
Duration of HIV diagnosis, y	6	12	1	14
CD4⁺ T-cell count, cells/mm³	650	974	868	1488
HIV-1 RNA levels, copies/mL	< 50	< 50	< 50	< 50
Single-copy assay, copies/mL	< 1	< 1	< 1	< 1
HLA class I B loci	40, 44	15, 57	44, 51	13, 57
CCR5 genotype	WT/Δ32	WT/WT	WT/WT	WT/WT
Neutralizing antibody activity, ID₅₀*	< 30	< 30	< 30	< 30
Colonic CD4⁺ T cells, %	NA	53.2	59.6	73.7
Colonic CD4⁺ T cells/g	NA	4.45 × 10⁶	3.35 × 10⁶	2.67 × 10⁷
Colonic CD4/CD8 ratio	NA	1.77	1.97	3.7

	Case 1	Case 2	Case 3	Case 4
Duration of HIV diagnosis, y	6	12	1	14
CD4⁺ T-cell count, cells/mm³	650	974	868	1488
HIV-1 RNA levels, copies/mL	< 50	< 50	< 50	< 50
Single-copy assay, copies/mL	< 1	< 1	< 1	< 1
HLA class I B loci	40, 44	15, 57	44, 51	13, 57
CCR5 genotype	WT/Δ32	WT/WT	WT/WT	WT/WT
Neutralizing antibody activity, ID₅₀*	< 30	< 30	< 30	< 30
Colonic CD4⁺ T cells, %	NA	53.2	59.6	73.7
Colonic CD4⁺ T cells/g	NA	4.45 × 10⁶	3.35 × 10⁶	2.67 × 10⁷
Colonic CD4/CD8 ratio	NA	1.77	1.97	3.7

WT indicates wild type; Δ32, CCR5 delta-32 mutation; ID₅₀, 50% inhibitory dose; and NA, not available.

Examined against a median of 5 viruses.