NK degranulation in nonstimulated conditions before cART in TB− IRIS patients
| . | HIV+/TB+ IRIS (n = 32)(1) . | HIV+/TB+ Non-IRIS (n = 67)(2) . | HIV+/TB− (n = 49) (3) . | HIV−/TB− (n = 30) (4) . | HIV−/TB+ (n = 28) (5) . | P < .005 . |
|---|---|---|---|---|---|---|
| Total CD107a | (1) vs (4) | |||||
| Median | 3.53 | 2.84 | 3.12 | 1.51 | 4.44 | (2) vs (4) |
| IQR | 1.57-6.10 | 1.55-3.99 | 2.07-4.18 | 1.00-2.83 | 2.85-7.47 | (2) vs (5) |
| CD107a+IFNγ− | (1) vs (3) | |||||
| Median | 3.06 | 2.31 | 1.67 | 1.03 | 3.77 | (1) vs (4) |
| IQR | 1.16-5.01 | 1.28-3.46 | 1.10-2.35 | 0.73-2.12 | 2.30-6.19 | (2) vs (4) |
| (2) vs (5) | ||||||
| CD107a+IFNγ+ | (1) vs (3) | |||||
| Median | 0.46 | 0.35 | 1.24 | 0.31 | 0.56 | (2) vs (3) |
| IQR | 0.28-0.83 | 0.20-0.66 | 0.72-1.74 | 0.24-0.89 | 0.36-1.11 | |
| CD107a−IFNγ+ | (1) vs (3) | |||||
| Median | 0.57 | 0.50 | 1.33 | 0.47 | 0.46 | (2) vs (3) |
| IQR | 0.27-1.16 | 0.29-0.77 | 0.70-2.23 | 0.31-0.69 | 0.14-0.88 | |
| Total IFNγ | (1) vs (3) | |||||
| Median | 1.18 | 0.92 | 2.76 | 0.88 | 1.24 | (2) vs (3) |
| IQR | 0.72-1.88 | 0.59-1.45 | 1.56-3.58 | 0.54-1.44 | 0.59-1.94 |
| . | HIV+/TB+ IRIS (n = 32)(1) . | HIV+/TB+ Non-IRIS (n = 67)(2) . | HIV+/TB− (n = 49) (3) . | HIV−/TB− (n = 30) (4) . | HIV−/TB+ (n = 28) (5) . | P < .005 . |
|---|---|---|---|---|---|---|
| Total CD107a | (1) vs (4) | |||||
| Median | 3.53 | 2.84 | 3.12 | 1.51 | 4.44 | (2) vs (4) |
| IQR | 1.57-6.10 | 1.55-3.99 | 2.07-4.18 | 1.00-2.83 | 2.85-7.47 | (2) vs (5) |
| CD107a+IFNγ− | (1) vs (3) | |||||
| Median | 3.06 | 2.31 | 1.67 | 1.03 | 3.77 | (1) vs (4) |
| IQR | 1.16-5.01 | 1.28-3.46 | 1.10-2.35 | 0.73-2.12 | 2.30-6.19 | (2) vs (4) |
| (2) vs (5) | ||||||
| CD107a+IFNγ+ | (1) vs (3) | |||||
| Median | 0.46 | 0.35 | 1.24 | 0.31 | 0.56 | (2) vs (3) |
| IQR | 0.28-0.83 | 0.20-0.66 | 0.72-1.74 | 0.24-0.89 | 0.36-1.11 | |
| CD107a−IFNγ+ | (1) vs (3) | |||||
| Median | 0.57 | 0.50 | 1.33 | 0.47 | 0.46 | (2) vs (3) |
| IQR | 0.27-1.16 | 0.29-0.77 | 0.70-2.23 | 0.31-0.69 | 0.14-0.88 | |
| Total IFNγ | (1) vs (3) | |||||
| Median | 1.18 | 0.92 | 2.76 | 0.88 | 1.24 | (2) vs (3) |
| IQR | 0.72-1.88 | 0.59-1.45 | 1.56-3.58 | 0.54-1.44 | 0.59-1.94 |
For all degranulation markers, the P value obtained from a Kruskal-Wallis test to compare the 5 groups was < .001; this allowed the 2-by-2 comparisons provided in this column. Only significant P values are indicated. Significantly different values are indicated in bold.
IQR indicates interquartile range.