Table 1

Demographic and clinical characteristics

HIV+/TB+ IRIS (n = 37)HIV+/TB+ non-IRIS (n = 91)HIV+/TB (n = 49)
Sex    
    Male 23 (62.2%) 57 (62.6%)  
    Female 14 (37.8%) 34 (37.4%)  
Median age, y (IRQ) 33 (28-38) 36 (31-44)  
CD4, cells/mm3    
    n (%) 37 (100.0) 91 (100.0) 34 (69.4) 
    Median (IQR) 27 (9-47) 27 (10-68) 85 (29-165)* 
Viral load, log copies/mL    
    n (%) 37 (100.0) 91 (100.0) 34 (65.4) 
    Median (IQR) 5.76 (5.41-5.99) 5.50 (5.10-5.95) 5.40 (4.77-5.71) 
BMI, kg/m2    
    Median (IQR) 16.0 (15.4-18.4) 16.8 (15.6-19.0)  
Identification    
    TB 33 (89.2) 62 (68.1)  
    Atypical myco 2 (2.2)  
    Unknown 4 (10.8) 27 (29.7)  
TB disseminated    
    Yes 16 (43.2) 16 (17.6)  
Total NK cells, %    
    n (%) 32 (86.5) 78 (85.7) 49 (100.0) 
    Median (IQR) 18.0 (10.0-28.3) 20.4 (11.4-25.4) 17.5 (12.5-22.5) 
HIV+/TB+ IRIS (n = 37)HIV+/TB+ non-IRIS (n = 91)HIV+/TB (n = 49)
Sex    
    Male 23 (62.2%) 57 (62.6%)  
    Female 14 (37.8%) 34 (37.4%)  
Median age, y (IRQ) 33 (28-38) 36 (31-44)  
CD4, cells/mm3    
    n (%) 37 (100.0) 91 (100.0) 34 (69.4) 
    Median (IQR) 27 (9-47) 27 (10-68) 85 (29-165)* 
Viral load, log copies/mL    
    n (%) 37 (100.0) 91 (100.0) 34 (65.4) 
    Median (IQR) 5.76 (5.41-5.99) 5.50 (5.10-5.95) 5.40 (4.77-5.71) 
BMI, kg/m2    
    Median (IQR) 16.0 (15.4-18.4) 16.8 (15.6-19.0)  
Identification    
    TB 33 (89.2) 62 (68.1)  
    Atypical myco 2 (2.2)  
    Unknown 4 (10.8) 27 (29.7)  
TB disseminated    
    Yes 16 (43.2) 16 (17.6)  
Total NK cells, %    
    n (%) 32 (86.5) 78 (85.7) 49 (100.0) 
    Median (IQR) 18.0 (10.0-28.3) 20.4 (11.4-25.4) 17.5 (12.5-22.5) 

IQR indicates interquartile range.

*

P < .001 when comparing HIV+/TB+ IRIS and HIV+/TB+ non-IRIS with HIV+/TB.

P = .004 when comparing HIV+/TB+ IRIS with HIV+/TB.

P = .002 when comparing HIV+/TB+ IRIS with HIV+/TB+ non-IRIS.

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