Table 4

Complete response considering type of treatment (R-ICE vs R-DHAP) and phenotype characteristics including cell of origin based on the Hans algorithm and MYC aberration

TreatmentComplete response
P(X2)
R-ICE
R-DHAP
n = 78 (%)n = 83 (%)
Patients analyzed by FISH 29 (37) 35 (42) .3187 
Hans COO    
    GC 24 (31) 41 (49) .0348 
    Non GC 37 (47) 32 (38) .2931 
MYC aberration    
    Presence 20 (26) 19 (23) .8268 
    Absence 27 (35) 45 (54) .0250 
TreatmentComplete response
P(X2)
R-ICE
R-DHAP
n = 78 (%)n = 83 (%)
Patients analyzed by FISH 29 (37) 35 (42) .3187 
Hans COO    
    GC 24 (31) 41 (49) .0348 
    Non GC 37 (47) 32 (38) .2931 
MYC aberration    
    Presence 20 (26) 19 (23) .8268 
    Absence 27 (35) 45 (54) .0250 

COO indicates cell of origin; GC, germinal center; R-ICE, rituximab, ifosfamide, etoposide, carboplatin; and R-DHAP, rituximab, dexamethasone, aracytine, cisplatin.

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