Adverse events at least possibly related to the treatment regimen
| Toxicity . | Grade* . | No. of patients experiencing adverse events at this grade . | “Possible” or greater attribution . |
|---|---|---|---|
| Leukopenia | 4 | 1 | CY |
| Lymphopenia | 4 | 1 | CY, IL-2 |
| Neutropenia | 4 | 1 | CY, IL-2 |
| Lymphopenia | 3 | 2 | CY |
| Thrombocytopenia | 3 | 1 | CY, IL-2 |
| Cellulitis | 3 | 1 | CY, IL-2 |
| Hypoxemia | 3 | 1 | T cells, IL-2 |
| Anemia | 2 | 1 | CY |
| Leukopenia | 2 | 2 | CY |
| Lymphopenia | 2 | 1 | CY |
| Neutropenia | 2 | 1 | CY |
| Thrombocytopenia | 2 | 1 | Apheresis |
| Orthostatic hypotension | 2 | 1 | T cells |
| Fatigue | 2 | 2 | CY, IL-2 |
| Fever | 2 | 1 | T cells, IL-2 |
| Night sweats | 2 | 1 | IL-2 |
| Injection site reaction | 2 | 1 | IL-2 |
| Headache | 2 | 1 | IL-2 |
| Anemia | 1 | 1 | CY, IL-2 |
| Lymphopenia | 1 | 1 | CY |
| Neutropenia | 1 | 2 | CY, IL-2 |
| Thrombocytopenia | 1 | 2 | CY, IL-2 |
| Chills | 1 | 1 | T cells, IL-2 |
| Fatigue | 1 | 2 | CY, IL-2 |
| Rigors | 1 | 1 | IL-2 |
| Alopecia | 1 | 3 | CY |
| Injection site reaction | 1 | 1 | IL-2 |
| Injection site redness | 1 | 1 | IL-2 |
| Diarrhea | 1 | 2 | CY, IL-2 |
| Nausea | 1 | 2 | CY |
| ALT elevation | 1 | 1 | CY |
| AST elevation | 1 | 1 | CY |
| Dyspnea | 1 | 2 | IL-2 |
| Flu-like syndrome | 1 | 1 | IL-2 |
| Toxicity . | Grade* . | No. of patients experiencing adverse events at this grade . | “Possible” or greater attribution . |
|---|---|---|---|
| Leukopenia | 4 | 1 | CY |
| Lymphopenia | 4 | 1 | CY, IL-2 |
| Neutropenia | 4 | 1 | CY, IL-2 |
| Lymphopenia | 3 | 2 | CY |
| Thrombocytopenia | 3 | 1 | CY, IL-2 |
| Cellulitis | 3 | 1 | CY, IL-2 |
| Hypoxemia | 3 | 1 | T cells, IL-2 |
| Anemia | 2 | 1 | CY |
| Leukopenia | 2 | 2 | CY |
| Lymphopenia | 2 | 1 | CY |
| Neutropenia | 2 | 1 | CY |
| Thrombocytopenia | 2 | 1 | Apheresis |
| Orthostatic hypotension | 2 | 1 | T cells |
| Fatigue | 2 | 2 | CY, IL-2 |
| Fever | 2 | 1 | T cells, IL-2 |
| Night sweats | 2 | 1 | IL-2 |
| Injection site reaction | 2 | 1 | IL-2 |
| Headache | 2 | 1 | IL-2 |
| Anemia | 1 | 1 | CY, IL-2 |
| Lymphopenia | 1 | 1 | CY |
| Neutropenia | 1 | 2 | CY, IL-2 |
| Thrombocytopenia | 1 | 2 | CY, IL-2 |
| Chills | 1 | 1 | T cells, IL-2 |
| Fatigue | 1 | 2 | CY, IL-2 |
| Rigors | 1 | 1 | IL-2 |
| Alopecia | 1 | 3 | CY |
| Injection site reaction | 1 | 1 | IL-2 |
| Injection site redness | 1 | 1 | IL-2 |
| Diarrhea | 1 | 2 | CY, IL-2 |
| Nausea | 1 | 2 | CY |
| ALT elevation | 1 | 1 | CY |
| AST elevation | 1 | 1 | CY |
| Dyspnea | 1 | 2 | IL-2 |
| Flu-like syndrome | 1 | 1 | IL-2 |
ALT indicates alanine aminotransferase; and AST, aspartate aminotransferase.
The maximum grade experienced for the corresponding toxicity for a given patient.