Molecular associations of splice gene mutations (Fisher exact test)
| . | TET2mut (n = 54) . | ASXL1mut (n = 37) . | DNMT3Amut (n = 26) . | RUNX1mut (n = 16) . | TP53mut (n = 13) . | IDH1/2mut (n = 12) . | CBLmut (n = 11) . | JAK2mut (n = 9) . | EZH2mut (n = 7) . | ETV6mut (n = 2) . | NRASmut (n = 2) . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SF3B1mut (n = 37) | 9 | 4 | 13 (P < .001) | 3 | 1 | 1 | 1 | 3 | 1 | 0 | 0 |
| SRSF2mut (n = 25) | 11 (P = .02) | 6 | 4 | 4 (P = .09) | 1 | 3 | 3 | 0 | 0 | 0 | 0 |
| ZRSR2mut (n = 25) | 14 (P < .001) | 5 | 1 | 3 | 0 | 3 | 1 | 0 | 1 | 0 | 0 |
| U2AF35mut (n = 12) | 1 | 5 (P = .03) | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
| . | TET2mut (n = 54) . | ASXL1mut (n = 37) . | DNMT3Amut (n = 26) . | RUNX1mut (n = 16) . | TP53mut (n = 13) . | IDH1/2mut (n = 12) . | CBLmut (n = 11) . | JAK2mut (n = 9) . | EZH2mut (n = 7) . | ETV6mut (n = 2) . | NRASmut (n = 2) . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SF3B1mut (n = 37) | 9 | 4 | 13 (P < .001) | 3 | 1 | 1 | 1 | 3 | 1 | 0 | 0 |
| SRSF2mut (n = 25) | 11 (P = .02) | 6 | 4 | 4 (P = .09) | 1 | 3 | 3 | 0 | 0 | 0 | 0 |
| ZRSR2mut (n = 25) | 14 (P < .001) | 5 | 1 | 3 | 0 | 3 | 1 | 0 | 1 | 0 | 0 |
| U2AF35mut (n = 12) | 1 | 5 (P = .03) | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |