Patient demographic characteristics and key baseline values
| Characteristic . | FBS0701 14.5 mg/kg per d (N = 24) . | FBS0701 29 mg/kg per d (N = 27) . | P . | Total (N = 51) . |
|---|---|---|---|---|
| Age (y) | .8946 | |||
| N | 24 | 27 | 51 | |
| Mean (SD) | 28.7 (8.60) | 28.4 (7.11) | 28.5 (7.77) | |
| Median | 26.5 | 27.0 | 27.0 | |
| Range | 19-48 | 18-47 | 18-48 | |
| Sex | 1.0000 | |||
| Male | 12 (50.0%) | 13 (48.1%) | 25 (49.0%) | |
| Female | 12 (50.0%) | 14 (51.9%) | 26 (51.0%) | |
| Race | .8256 | |||
| Asian | 6 (25.0%) | 9 (33.3%) | 15 (29.4%) | |
| Black or white | 2 (8.3%) | 2 (7.4%) | 4 (7.8%) | |
| White | 16 (66.7%) | 16 (59.3%) | 32 (62.7%) | |
| LIC, mg/g liver, dry weight | ||||
| Baseline (mean ± SD) | 13.2 (6.64) | 13.9 (7.82) | ||
| Serum ferritin, ng/mL* | ||||
| Baseline (median) | 2564 | 2624 | ||
| Baseline (mean ± SD) | 3335 (2644) | 3162 (1682) | ||
| Mean of previous (3) transfusions, pretransfusion hemoglobin, g/dL | .2813 | |||
| N | 24 | 27 | 51 | |
| Mean (SD) | 9.6 (0.56) | 9.8 (0.79) | 9.7 (0.69) | |
| Median | 9.6 | 9.8 | 9.6 | |
| Range | 8.2-10.4 | 8.3-11.4 | 8.2-11.4 | |
| Daily transfusion iron intake, mg/kg, mean (range)* | 0.36 (0.22-0.84) | 0.38 (0.17-0.60) | ||
| Weight, kg | .1771 | |||
| N | 24 | 27 | 51 | |
| Mean (SD) | 57.0 (11.22) | 52.9 (10.07) | 54.8 (10.71) |
| Characteristic . | FBS0701 14.5 mg/kg per d (N = 24) . | FBS0701 29 mg/kg per d (N = 27) . | P . | Total (N = 51) . |
|---|---|---|---|---|
| Age (y) | .8946 | |||
| N | 24 | 27 | 51 | |
| Mean (SD) | 28.7 (8.60) | 28.4 (7.11) | 28.5 (7.77) | |
| Median | 26.5 | 27.0 | 27.0 | |
| Range | 19-48 | 18-47 | 18-48 | |
| Sex | 1.0000 | |||
| Male | 12 (50.0%) | 13 (48.1%) | 25 (49.0%) | |
| Female | 12 (50.0%) | 14 (51.9%) | 26 (51.0%) | |
| Race | .8256 | |||
| Asian | 6 (25.0%) | 9 (33.3%) | 15 (29.4%) | |
| Black or white | 2 (8.3%) | 2 (7.4%) | 4 (7.8%) | |
| White | 16 (66.7%) | 16 (59.3%) | 32 (62.7%) | |
| LIC, mg/g liver, dry weight | ||||
| Baseline (mean ± SD) | 13.2 (6.64) | 13.9 (7.82) | ||
| Serum ferritin, ng/mL* | ||||
| Baseline (median) | 2564 | 2624 | ||
| Baseline (mean ± SD) | 3335 (2644) | 3162 (1682) | ||
| Mean of previous (3) transfusions, pretransfusion hemoglobin, g/dL | .2813 | |||
| N | 24 | 27 | 51 | |
| Mean (SD) | 9.6 (0.56) | 9.8 (0.79) | 9.7 (0.69) | |
| Median | 9.6 | 9.8 | 9.6 | |
| Range | 8.2-10.4 | 8.3-11.4 | 8.2-11.4 | |
| Daily transfusion iron intake, mg/kg, mean (range)* | 0.36 (0.22-0.84) | 0.38 (0.17-0.60) | ||
| Weight, kg | .1771 | |||
| N | 24 | 27 | 51 | |
| Mean (SD) | 57.0 (11.22) | 52.9 (10.07) | 54.8 (10.71) |
Supplemental Figure 3 shows the transfusion burdens, and supplemental Figure 4 shows the ferritin levels in detail.