Multivariate logistic regression analysis of risk factors for complications after PBSC collection
. | Pain after G-CSF administration . | No. of aphereses > 1 . | Hypocalcemia after apheresis . | Any pain during PBSC procedure . | Cardiovascular complications after anesthesia . | Hospital stay ≥ 1 d . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | |
Donor age, y | .538 | .230 | .192 | .011 | 0.036 | .735 | ||||||
< 4 vs 4-8 | .290 | 2.77 (0.39-24.8) | .088 | 14.2 (0.68-285) | .332 | 0.41 (0.07-2.43) | .024 | 48 (1.7-912) | 0.213 | 8.34 (0.30-195) | .704 | 1.69 (0.11-24) |
< 4 vs > 8 | .997 | 0.56 (0.11-9.7) | .139 | 12.5 (0.44-292) | .428 | 0.33 (0.07-1.92) | .009 | 8.3 (1.7-51) | 0.044 | 33 (1.1-890) | .948 | 0.9 (0.03-21) |
Donor weight, kg | .925 | .350 | .341 | .328 | .254 | |||||||
< 20 vs 20-40 | .929 | 1.06 (0.26-4.5) | .302 | 1.6 (0.648.3) | .510 | 0.58 (0.12-3.7) | .185 | 5.8 (0.43-49) | 0.111 | 8.3 (0.6-96) | .372 | 3.57 (0.39-34) |
< 20 vs > 40 | .997 | 0.26 (0.03-19) | .086 | 12.5 (0.7-96) | .341 | 0.50 (0.12-1.85) | .866 | 1.1 (0.35-3.44) | .484 | 0.74 (0.24-2.21) | ||
D/R weight ratio < 0.75 | .431 | 0.46 (0.06-3.12) | .028 | 3.7 (1.14-11.2) | .635 | 0.76 (0.24-2.32) | .009 | 7.9 (1.68-36.9) | 0.392 | 1.58 (0.54-4.76) | .162 | 2.08 (0.76-5.8) |
Female vs male sex | .583 | 1.52 (0.64-4.58) | .052 | 0.42 (0.17-1.01) | .097 | 1.15 (0.88-3.2) | .959 | 0.98 (0.38-2.49) | 0.785 | 1.14 (0.45-2.84) | .380 | 1.52 (0.60-3.89) |
WBC before apheresis > 50 × 109/L | .738 | 1.41 (0.62-4.28) | .004 | 0.25 (0.10-0.64) | .647 | 0.58 (0.09-2.13) | .237 | 11.45 (0.04-82.19) | 0.679 | 0.81 (0.31-2.17) | .146 | 2.10 (0.77-5.73) |
No. of aphereses > 1 vs 1 | .933 | 1.97 (0.27-11.06) | ND | ND | .202 | 2.55 (0.61-10.72) | .469 | 1.93 (0.36-11.45) | ND | ND | .685 | 1.25 (0.42-3.71) |
. | Pain after G-CSF administration . | No. of aphereses > 1 . | Hypocalcemia after apheresis . | Any pain during PBSC procedure . | Cardiovascular complications after anesthesia . | Hospital stay ≥ 1 d . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | |
Donor age, y | .538 | .230 | .192 | .011 | 0.036 | .735 | ||||||
< 4 vs 4-8 | .290 | 2.77 (0.39-24.8) | .088 | 14.2 (0.68-285) | .332 | 0.41 (0.07-2.43) | .024 | 48 (1.7-912) | 0.213 | 8.34 (0.30-195) | .704 | 1.69 (0.11-24) |
< 4 vs > 8 | .997 | 0.56 (0.11-9.7) | .139 | 12.5 (0.44-292) | .428 | 0.33 (0.07-1.92) | .009 | 8.3 (1.7-51) | 0.044 | 33 (1.1-890) | .948 | 0.9 (0.03-21) |
Donor weight, kg | .925 | .350 | .341 | .328 | .254 | |||||||
< 20 vs 20-40 | .929 | 1.06 (0.26-4.5) | .302 | 1.6 (0.648.3) | .510 | 0.58 (0.12-3.7) | .185 | 5.8 (0.43-49) | 0.111 | 8.3 (0.6-96) | .372 | 3.57 (0.39-34) |
< 20 vs > 40 | .997 | 0.26 (0.03-19) | .086 | 12.5 (0.7-96) | .341 | 0.50 (0.12-1.85) | .866 | 1.1 (0.35-3.44) | .484 | 0.74 (0.24-2.21) | ||
D/R weight ratio < 0.75 | .431 | 0.46 (0.06-3.12) | .028 | 3.7 (1.14-11.2) | .635 | 0.76 (0.24-2.32) | .009 | 7.9 (1.68-36.9) | 0.392 | 1.58 (0.54-4.76) | .162 | 2.08 (0.76-5.8) |
Female vs male sex | .583 | 1.52 (0.64-4.58) | .052 | 0.42 (0.17-1.01) | .097 | 1.15 (0.88-3.2) | .959 | 0.98 (0.38-2.49) | 0.785 | 1.14 (0.45-2.84) | .380 | 1.52 (0.60-3.89) |
WBC before apheresis > 50 × 109/L | .738 | 1.41 (0.62-4.28) | .004 | 0.25 (0.10-0.64) | .647 | 0.58 (0.09-2.13) | .237 | 11.45 (0.04-82.19) | 0.679 | 0.81 (0.31-2.17) | .146 | 2.10 (0.77-5.73) |
No. of aphereses > 1 vs 1 | .933 | 1.97 (0.27-11.06) | ND | ND | .202 | 2.55 (0.61-10.72) | .469 | 1.93 (0.36-11.45) | ND | ND | .685 | 1.25 (0.42-3.71) |
ND indicates not done.