Correlation of low versus high IL-10 pretreatment and DLBCL patient disease characteristics
| . | Low IL-10 (n = 35) . | High IL-10 (n = 35) . | P . |
|---|---|---|---|
| Age ≥ 60 y | 20 (50%) | 25 (61%) | .32 |
| Female sex | 18 (45%) | 13 (32%) | .22 |
| PS 0-1 | 36 (90%) | 34 (83%) | .35 |
| Stage III-IV | 30 (75%) | 36 (86%) | .14 |
| Elevated lactate dehydrogenase | 9 (22%) | 20 (50%) | .0085 |
| ≥ 2 extranodal sites | 9 (23%) | 13 (32%) | .35 |
| International Prognostic Index score | |||
| 0-1 | 16 (40%) | 5 (12%) | .027 |
| 2 | 9 (23%) | 9 (22%) | |
| 3 | 11 (28%) | 20 (49%) | |
| 4-5 | 4 (10%) | 7 (17%) | |
| 0-2 | 25 (63%) | 14 (34%) | .011 |
| 3-5 | 15 (38%) | 27 (66%) | |
| B symptoms | 21 (51%) | 27 (68%) | .14 |
| Bulky disease (> 10 cm) | 5 (13%) | 9 (22%) | .26 |
| . | Low IL-10 (n = 35) . | High IL-10 (n = 35) . | P . |
|---|---|---|---|
| Age ≥ 60 y | 20 (50%) | 25 (61%) | .32 |
| Female sex | 18 (45%) | 13 (32%) | .22 |
| PS 0-1 | 36 (90%) | 34 (83%) | .35 |
| Stage III-IV | 30 (75%) | 36 (86%) | .14 |
| Elevated lactate dehydrogenase | 9 (22%) | 20 (50%) | .0085 |
| ≥ 2 extranodal sites | 9 (23%) | 13 (32%) | .35 |
| International Prognostic Index score | |||
| 0-1 | 16 (40%) | 5 (12%) | .027 |
| 2 | 9 (23%) | 9 (22%) | |
| 3 | 11 (28%) | 20 (49%) | |
| 4-5 | 4 (10%) | 7 (17%) | |
| 0-2 | 25 (63%) | 14 (34%) | .011 |
| 3-5 | 15 (38%) | 27 (66%) | |
| B symptoms | 21 (51%) | 27 (68%) | .14 |
| Bulky disease (> 10 cm) | 5 (13%) | 9 (22%) | .26 |
Low IL-10 was < 26.15 pg/mL; high, > 26.15 pg/mL. All values are n (%).