Table 2

Results of the treatment with standard-dose chemotherapy

Study typeReferenceNo. of patientsNo. operatedNo. chemotherapy-treatedType of chemotherapyOverall response (complete response), %Median survival, mo (range)
Retrospective 62  24 12 11 CHOP, BACOP, ProMACE-MOPP NG (NG) 10 (0-196) 
Retrospective 16  31 25 24 CHOP, VAMP, PEACE-BOM 58 (32) 7.5 (0-83) 
Retrospective 61  Hyper-CVAD 100 (100) 34 
Retrospective 31  10 10 CHOP NG (50) 5 (1-12) 
Retrospective 64  54 49 31 CHOP, CHOP-like 32 (32) 7 (0-140) 
Prospective 58  23 13 15 CHOP NG (35) 7 (NG) 
Prospective 63  10 10 10 CHOEP 60 (30) 7 (2-16) 
Study typeReferenceNo. of patientsNo. operatedNo. chemotherapy-treatedType of chemotherapyOverall response (complete response), %Median survival, mo (range)
Retrospective 62  24 12 11 CHOP, BACOP, ProMACE-MOPP NG (NG) 10 (0-196) 
Retrospective 16  31 25 24 CHOP, VAMP, PEACE-BOM 58 (32) 7.5 (0-83) 
Retrospective 61  Hyper-CVAD 100 (100) 34 
Retrospective 31  10 10 CHOP NG (50) 5 (1-12) 
Retrospective 64  54 49 31 CHOP, CHOP-like 32 (32) 7 (0-140) 
Prospective 58  23 13 15 CHOP NG (35) 7 (NG) 
Prospective 63  10 10 10 CHOEP 60 (30) 7 (2-16) 

BACOP indicates bleomycin, doxorubicin, cyclophosphamide, vincristine, prednisone; C, complete response; CHOP, cyclophosphamide, doxorubicin, vincristine, prenisone; CHOEP, same drugs as in CHOP plus etoposide; CT, chemotherapy; Hyper-CVAD: cyclophosphamide, vincristine, dexamethasone, methotrexate, cytarabine; NG, not given; O, overall response; PEACE-BOM, prednisolone, etoposide, doxorubicin, cyclophosphamide-bleomycin, vincristine, methotrexate; ProMACE-MOPP, prednisone, doxorubicin, cyclophosphamide, etoposide, mechlorethamine, vincristine, procarbazine; and VAMP, vincristine, doxorubicin, high-dose methotrexate, prednisolone.

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