Table 4

Univariate analyses of outcome by prognostic factors

Prognostic factor% No HDM 5-year EFS ± SE (n)% HDM 5-year EFS ± SE (n)Hazard ratioP
T-ALL     
    Age, y     
        Younger than 10 72.9 ± 4.9 (85) 85.6 ± 4.1 (78) 1.73 .01 
        10 or older 60.6 ± 6.3 (66) 72.8 ± 5.6 (70)   
    WBC     
        < 50 81.9 ± 5.1 (61) 81.2 ± 5.2 (64) 1.85 .01 
        ≥ 50 57.7 ± 5.4 (90) 78.4 ± 4.6 (84)   
    NCI risk     
        Standard 83.9 ± 6.7 (31) 86.8 ± 5.8 (38) 2.21 .01 
        High 63.3 ± 4.6 (120) 77.1 ± 4.2(110)   
    Sex     
        Male 61.4 ± 4.8 (109) 79.1 ± 4.0(111) 0.56 .03 
        Female 83.3 ± 5.8 (42) 80.7 ± 6.8 (37)   
    Race     
        White 68.0 ± 4.5 (113) 81.8 ± 3.7(116)   
        Black 65.6 ± 8.6 (32) 64.9 ± 11.6(23) 1.49 .33 
        Other 66.7 ± 19.3 (6) 88.9 ± 10.5 (9) 0.99  
T-NHL     
    Stage III 88.1 ± 5.1 (43) 79.9 ± 6.2 (45) 0.69 .43 
    Stage IV 87.0 ± 7.4 (23) 88.0 ± 7.2 (26)   
Prognostic factor% No HDM 5-year EFS ± SE (n)% HDM 5-year EFS ± SE (n)Hazard ratioP
T-ALL     
    Age, y     
        Younger than 10 72.9 ± 4.9 (85) 85.6 ± 4.1 (78) 1.73 .01 
        10 or older 60.6 ± 6.3 (66) 72.8 ± 5.6 (70)   
    WBC     
        < 50 81.9 ± 5.1 (61) 81.2 ± 5.2 (64) 1.85 .01 
        ≥ 50 57.7 ± 5.4 (90) 78.4 ± 4.6 (84)   
    NCI risk     
        Standard 83.9 ± 6.7 (31) 86.8 ± 5.8 (38) 2.21 .01 
        High 63.3 ± 4.6 (120) 77.1 ± 4.2(110)   
    Sex     
        Male 61.4 ± 4.8 (109) 79.1 ± 4.0(111) 0.56 .03 
        Female 83.3 ± 5.8 (42) 80.7 ± 6.8 (37)   
    Race     
        White 68.0 ± 4.5 (113) 81.8 ± 3.7(116)   
        Black 65.6 ± 8.6 (32) 64.9 ± 11.6(23) 1.49 .33 
        Other 66.7 ± 19.3 (6) 88.9 ± 10.5 (9) 0.99  
T-NHL     
    Stage III 88.1 ± 5.1 (43) 79.9 ± 6.2 (45) 0.69 .43 
    Stage IV 87.0 ± 7.4 (23) 88.0 ± 7.2 (26)   

T-ALL indicates T-cell acute lymphoblastic leukemia; T-NHL, T-cell lymphoblastic non-Hodgkin lymphoma; EFS, event-free survival; NCI, National Cancer Institute; and HDM, high-dose methotrexate.

Close Modal

or Create an Account

Close Modal
Close Modal