Table 3 Distribution of treatment... | American Society of Hematology

Table 3

Distribution of treatment failures (randomized patients only)

	T-ALL		T-NHL		Total
	No HDM (n = 151)	HDM (n = 148)	No HDM (n = 66)	HDM (n = 71)	No HDM (n = 217)	HDM (n = 219)
Total failures	50	35	9	14	59	49
Induction failures	14	7	1	1	15	8
Induction deaths	1	2	0	0	1	2
Relapse	28	20	5	10	33	30
Marrow only	4	8	1	1	5	9
Marrow + CNS	7	1	0	0	7	1
Marrow + testicular	0	0	0	1	0	1
Marrow + Mediastinal	1	2	0	1	1	3
Marrow + other	1*	1†	0	1*	1	2
Isolated CNS	11	7‡	1	2	12	9
Isolated testicular	1	1	0	0	1	1
Mediastinal ± other	0	0	2§	3¶	2	3
Lymph	0	0	1	1	1	1
Unspecified	3	0	0	0	3	0
Second malignancy	4	4	2	1	6	5
Remission deaths	3	2	1	2	4	4

	T-ALL		T-NHL		Total
	No HDM (n = 151)	HDM (n = 148)	No HDM (n = 66)	HDM (n = 71)	No HDM (n = 217)	HDM (n = 219)
Total failures	50	35	9	14	59	49
Induction failures	14	7	1	1	15	8
Induction deaths	1	2	0	0	1	2
Relapse	28	20	5	10	33	30
Marrow only	4	8	1	1	5	9
Marrow + CNS	7	1	0	0	7	1
Marrow + testicular	0	0	0	1	0	1
Marrow + Mediastinal	1	2	0	1	1	3
Marrow + other	1*	1†	0	1*	1	2
Isolated CNS	11	7‡	1	2	12	9
Isolated testicular	1	1	0	0	1	1
Mediastinal ± other	0	0	2§	3¶	2	3
Lymph	0	0	1	1	1	1
Unspecified	3	0	0	0	3	0
Second malignancy	4	4	2	1	6	5
Remission deaths	3	2	1	2	4	4

T-ALL indicates T-cell acute lymphoblastic leukemia; T-NHL, T-cell lymphoblastic non-Hodgkin lymphoma; and HDM, high-dose methotrexate.

One lymph.

One spleen.

One eye.

One pleura.

One lung.