Table 1

Incidence of SPMs in patients treated with lenalidomide-based therapy

Treatment duration
< 12 mo (n = 3149)≥ 12 mo (n = 697)≥ 18 mo (n = 450)≥ 24 mo (n = 313)≥ 36 mo (n = 130)All patients (N = 3846)
SPM IR 2.03 2.12 2.13 2.35 2.45 2.08 
Patient-years 1281.20 1463.35 1175.78 937.28 490.52 2744.55 
95% CI 1.38-2.98 1.49-3.01 1.44-3.15 1.55-3.56 1.39-4.31 1.60-2.60 
Treatment duration
< 12 mo (n = 3149)≥ 12 mo (n = 697)≥ 18 mo (n = 450)≥ 24 mo (n = 313)≥ 36 mo (n = 130)All patients (N = 3846)
SPM IR 2.03 2.12 2.13 2.35 2.45 2.08 
Patient-years 1281.20 1463.35 1175.78 937.28 490.52 2744.55 
95% CI 1.38-2.98 1.49-3.01 1.44-3.15 1.55-3.56 1.39-4.31 1.60-2.60 

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