Table 3 Baseline hemodynamics assessed... | American Society of Hematology

Table 3

Baseline hemodynamics assessed via right heart catheterization

	First baseline	Inhaled nitric oxide*	Second baseline*	30 min after sildenafil†	60 min after sildenafil†
Mean pulmonary artery pressure, mmHg	28 ± 11	26 ± 10‡	28 ± 12	27 ± 11	26 ± 12§
Mean right atrial pressure, mmHg	8 ± 4	8 ± 5	9 ± 5	8 ± 4§	8 ± 4§
Mean systemic arterial pressure, mmHg	88 ± 14	86 ± 14	90 ± 10	83 ± 13‡	84 ± 10‡
Mean pulmonary capillary wedge pressure, mmHg	13 ± 4	14 ± 6	14 ± 5	13 ± 5	12 ± 5§
Cardiac output, L/min	8.6 ± 3.3	8.5 ± 2.5	8.2 ± 2.8	9.0 ± 3.6	8.5 ± 2.9
Pulmonary vascular resistance, dyn/s/cm⁵	157 ± 122	120 ± 73‡	161 ± 120	143 ± 122	150 ± 119
Mixed venous oxygen saturation, %	65 ± 13	68 ± 9‡	66 ± 14	66 ± 12	65 ± 13

	First baseline	Inhaled nitric oxide*	Second baseline*	30 min after sildenafil†	60 min after sildenafil†
Mean pulmonary artery pressure, mmHg	28 ± 11	26 ± 10‡	28 ± 12	27 ± 11	26 ± 12§
Mean right atrial pressure, mmHg	8 ± 4	8 ± 5	9 ± 5	8 ± 4§	8 ± 4§
Mean systemic arterial pressure, mmHg	88 ± 14	86 ± 14	90 ± 10	83 ± 13‡	84 ± 10‡
Mean pulmonary capillary wedge pressure, mmHg	13 ± 4	14 ± 6	14 ± 5	13 ± 5	12 ± 5§
Cardiac output, L/min	8.6 ± 3.3	8.5 ± 2.5	8.2 ± 2.8	9.0 ± 3.6	8.5 ± 2.9
Pulmonary vascular resistance, dyn/s/cm⁵	157 ± 122	120 ± 73‡	161 ± 120	143 ± 122	150 ± 119
Mixed venous oxygen saturation, %	65 ± 13	68 ± 9‡	66 ± 14	66 ± 12	65 ± 13

Second baseline was taken 10 minutes after completion of the INO hemodynamic assessment; P value is a comparison to first baseline.

†

P compared with second baseline

‡

P < .01; and

§P < .05; P values are derived from a repeated measures mixed model including step/intervention as the effect of interest and the first baseline value as a covariate.

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