Table 4 Hematologic parameters before... | American Society of Hematology

Table 4

Hematologic parameters before therapy and grades 3-4 toxicity during therapy

Toxicity grade at baseline	Neutropenia		Anemia		Thrombocytopenia
Toxicity grade at baseline	No. of patients at baseline	Grade 3-4 during therapy, n	No. of patients at baseline	Grade 3-4 during therapy	No. of patients at baseline	Grade 3-4 during therapy, n
Thalidomide
0	39		4		22	1*
1	0		14	1*	9
2	5		21	1	4
3	0		5		6
4	0		0		3
Overall	44		44		44
Lenalidomide
0	39	7	6		28	5
1	0		16	1*	7	3
2	1	1*	17		3	1
3	1	1*	2		3	2*
4	0		0		0
Overall	41		41		41
Lenalidomide plus prednisone
0	35	18	4		28	1*
1	2	1	14	7	4
2	0		21	6	3
3	1		1		1	1*
4	2		0		4
Overall	40		40		40
P		.001		.001		.001

Toxicity grade at baseline	Neutropenia		Anemia		Thrombocytopenia
Toxicity grade at baseline	No. of patients at baseline	Grade 3-4 during therapy, n	No. of patients at baseline	Grade 3-4 during therapy	No. of patients at baseline	Grade 3-4 during therapy, n
Thalidomide
0	39		4		22	1*
1	0		14	1*	9
2	5		21	1	4
3	0		5		6
4	0		0		3
Overall	44		44		44
Lenalidomide
0	39	7	6		28	5
1	0		16	1*	7	3
2	1	1*	17		3	1
3	1	1*	2		3	2*
4	0		0		0
Overall	41		41		41
Lenalidomide plus prednisone
0	35	18	4		28	1*
1	2	1	14	7	4
2	0		21	6	3
3	1		1		1	1*
4	2		0		4
Overall	40		40		40
P		.001		.001		.001

Grade 4 only.