Table 1 Characteristics of CLL rAbs used... | American Society of Hematology

Table 1

Characteristics of CLL rAbs used in present investigation

Recombinant IgG	IGHV gene	IGHD gene	IGHJ gene	% germ line identity	HCDR3 sequence	IGKV/IGLV gene	% germ line identity	LCDR3 sequence
CLL69A	IGHV1-69	D3-16	JH3	100	GGIYDYVWGSYRPNDAFDI	IGKV3-20	100	QQYGSSPGT
CLL69B	IGHV1-69	D2-02	JH6	100	MRPDIVVVPAAISYYYGMDV	IGKV1-39	100	QQSYSTPRT
CLL69D	IGHV1-69	D2-02	JH6	100	GGDIVVVPAAMSYYYYGMDV	IGKV3-11	100	QQRSNT
CLL3-21U1	IGHV3-21		JH6	99	DQNGMDV	IGLV3-21	99.3	QVWDAGSDHPWV
CLL3-21U2	IGHV3-21	D6-13	JH4	100	DPSFYSSSWTLFDY	IGKV3-20	100	QQYGSSPLT
CLL3-21M1	IGHV3-21		JH6	95.4	DGNGMDV	IGLV3-21	97	QVWDSGSDHPWV
CLL4-39A	IGHV4-39	D2-02	JH6	100	HRLGYCSSTSCYYYYYGMDV	IGLV1-40	99.7	QSYDSSLSVV
GW21	IGHV1-69	D5-24	JH4	99.7	DGEMATDDHFDY	IGLV1-40	99.7	QSYDSSLSVV
MU08	IGHV1-69	D3-10	JH5	100	AGYGSGTYWFDP	IGLV1-40	99.7	QSYDSSLSVV

Recombinant IgG	IGHV gene	IGHD gene	IGHJ gene	% germ line identity	HCDR3 sequence	IGKV/IGLV gene	% germ line identity	LCDR3 sequence
CLL69A	IGHV1-69	D3-16	JH3	100	GGIYDYVWGSYRPNDAFDI	IGKV3-20	100	QQYGSSPGT
CLL69B	IGHV1-69	D2-02	JH6	100	MRPDIVVVPAAISYYYGMDV	IGKV1-39	100	QQSYSTPRT
CLL69D	IGHV1-69	D2-02	JH6	100	GGDIVVVPAAMSYYYYGMDV	IGKV3-11	100	QQRSNT
CLL3-21U1	IGHV3-21		JH6	99	DQNGMDV	IGLV3-21	99.3	QVWDAGSDHPWV
CLL3-21U2	IGHV3-21	D6-13	JH4	100	DPSFYSSSWTLFDY	IGKV3-20	100	QQYGSSPLT
CLL3-21M1	IGHV3-21		JH6	95.4	DGNGMDV	IGLV3-21	97	QVWDSGSDHPWV
CLL4-39A	IGHV4-39	D2-02	JH6	100	HRLGYCSSTSCYYYYYGMDV	IGLV1-40	99.7	QSYDSSLSVV
GW21	IGHV1-69	D5-24	JH4	99.7	DGEMATDDHFDY	IGLV1-40	99.7	QSYDSSLSVV
MU08	IGHV1-69	D3-10	JH5	100	AGYGSGTYWFDP	IGLV1-40	99.7	QSYDSSLSVV