Body weight and hemodynamic parameters
Genotype . | Cbs+/+ . | Tg-I278T Cbs+/+ . | Tg-I278T Cbs−/− . |
---|---|---|---|
Body weight, g | 28.5 ± 1.8 | 28.2 ± 1.5 | 23.07 ± 0.8* |
Mean systemic arterial blood pressure | 71.8 ± 2.8 | 71.9 ± 2.5 | 66.1 ± 2.3 |
Carotid artery | |||
Baseline blood flow, mL/min | 0.35 ± .05 | 0.40 ± .05 | 0.45 ± .05 |
Total vessel area, μm2 | 105 382 ± 6149 | 104 821 ± 22 057 | 128 390 ± 1212 |
Luminal area, μm2 | 40 300 ± 12 180 | 35 396 ± 11 468 | 48 570 ± 3523 |
Genotype . | Cbs+/+ . | Tg-I278T Cbs+/+ . | Tg-I278T Cbs−/− . |
---|---|---|---|
Body weight, g | 28.5 ± 1.8 | 28.2 ± 1.5 | 23.07 ± 0.8* |
Mean systemic arterial blood pressure | 71.8 ± 2.8 | 71.9 ± 2.5 | 66.1 ± 2.3 |
Carotid artery | |||
Baseline blood flow, mL/min | 0.35 ± .05 | 0.40 ± .05 | 0.45 ± .05 |
Total vessel area, μm2 | 105 382 ± 6149 | 104 821 ± 22 057 | 128 390 ± 1212 |
Luminal area, μm2 | 40 300 ± 12 180 | 35 396 ± 11 468 | 48 570 ± 3523 |
P < .05 compared with Cbs+/+ and Tg-I278T Cbs+/+ mice (n = 6-14 in each group).