Table 3 Associations within subgroups... | American Society of Hematology

Table 3

Associations within subgroups between PROCR rs867186 genotypes and VTE or MI under the per-allele model in a random-effects meta-analysis

Subgroup	Included studies, n	Total cases, n	Total non-cases, n	OR	95% CI	I²	95% Uncertainty interval	Cochran Q P value
VTE
Candidate gene studies	9	2428	3968	1.19	1.07-1.34	15	0-51	.271
GWAS	2	1680	2529	1.28	1.02-1.61	29	0-74	.240
Studies of white subjects only	6	2405	3096	1.35	1.14-1.59	12	0-53	.321
Studies in HWE	9	3970	4653	1.28	1.16-1.41	10	0-46	.333
MI
Candidate gene studies	5	1576	4165	1.03	0.68-1.56	85	66-93	< .001
GWAS	11	31 018	74 171	0.93	0.89-0.98	36	0-68	.113
Studies of white subjects only	14	28 086	73 728	0.93	0.86-1.00	66	40-81	< .001
Studies in HWE	15	31 905	77 639	0.95	0.90-1.01	54	16-74	.007
Studies of subjects with a history of MI only	6	5730	7292	0.87	0.75-1.00	64	14-85	.016

Subgroup	Included studies, n	Total cases, n	Total non-cases, n	OR	95% CI	I²	95% Uncertainty interval	Cochran Q P value
VTE
Candidate gene studies	9	2428	3968	1.19	1.07-1.34	15	0-51	.271
GWAS	2	1680	2529	1.28	1.02-1.61	29	0-74	.240
Studies of white subjects only	6	2405	3096	1.35	1.14-1.59	12	0-53	.321
Studies in HWE	9	3970	4653	1.28	1.16-1.41	10	0-46	.333
MI
Candidate gene studies	5	1576	4165	1.03	0.68-1.56	85	66-93	< .001
GWAS	11	31 018	74 171	0.93	0.89-0.98	36	0-68	.113
Studies of white subjects only	14	28 086	73 728	0.93	0.86-1.00	66	40-81	< .001
Studies in HWE	15	31 905	77 639	0.95	0.90-1.01	54	16-74	.007
Studies of subjects with a history of MI only	6	5730	7292	0.87	0.75-1.00	64	14-85	.016