Table 2 Associations between PROCR... | American Society of Hematology

Table 2

Associations between PROCR rs867186 genotypes and VTE or MI in a random-effects meta-analysis

Genotype contrast	Included studies, n	Total cases, n	Total non-cases, n	OR	95% CI	I²	95% Uncertainty interval	Cochran Q P value
VTE
Per-allele model	11	4821	6070	1.22	1.11-1.33	20	0-52	.197
AG versus AA	11	4736	6010	1.21	1.05-1.40	43	0-72	.063
GG versus AA	11	3825	4979	1.81	1.29-2.56	0	0-46	.694
AG + GG versus AA (dominant)	11	4821	6070	1.25	1.08-1.44	47	0-74	.041
GG versus AG + AA (recessive)	11	4821	6070	1.76	1.24-2.48	0	0-42	.739
MI
Per-allele model	16	32 594	78 336	0.94	0.88-1.00	65	40-79	< .001
AG versus AA	14	16 850	42 919	0.96	0.86-1.06	67	43-81	< .001
GG versus AA	14	14 012	35 671	0.87	0.72-1.06	0	0-53	.502
AG + GG versus AA (dominant)	14	16 998	43 344	0.95	0.86-1.05	65	37-80	< .001
GG versus AG + AA (recessive)	14	16 998	43 344	0.88	0.72-1.06	0	0-55	.462

Genotype contrast	Included studies, n	Total cases, n	Total non-cases, n	OR	95% CI	I²	95% Uncertainty interval	Cochran Q P value
VTE
Per-allele model	11	4821	6070	1.22	1.11-1.33	20	0-52	.197
AG versus AA	11	4736	6010	1.21	1.05-1.40	43	0-72	.063
GG versus AA	11	3825	4979	1.81	1.29-2.56	0	0-46	.694
AG + GG versus AA (dominant)	11	4821	6070	1.25	1.08-1.44	47	0-74	.041
GG versus AG + AA (recessive)	11	4821	6070	1.76	1.24-2.48	0	0-42	.739
MI
Per-allele model	16	32 594	78 336	0.94	0.88-1.00	65	40-79	< .001
AG versus AA	14	16 850	42 919	0.96	0.86-1.06	67	43-81	< .001
GG versus AA	14	14 012	35 671	0.87	0.72-1.06	0	0-53	.502
AG + GG versus AA (dominant)	14	16 998	43 344	0.95	0.86-1.05	65	37-80	< .001
GG versus AG + AA (recessive)	14	16 998	43 344	0.88	0.72-1.06	0	0-55	.462