Table 1

Comparison of disease complications during follow-up in initial fibrotic versus non-fibrotic PV patients

EventsNumber of events (%)Incidence per 100 patient-yearsIRRP5-year cumulative incidence, %10-year cumulative incidence, %15-year cumulative incidence, %
Thrombosis        
    No BM fibrosis 75 (17) 2.7 0.4 .03 14.6 20.3 32.0 
    BM fibrosis ≥ 1 5 (7) 1.1   1.8 14.1 20.3 
Progression to overt myelofibrosis        
    No BM fibrosis 25 (6) 0.8 2.7 .01 1.3 6.9 15.4 
    BM fibrosis ≥ 1 10 (14) 2.2   7.8 22.0 29.1 
Leukemic transformation        
    No BM fibrosis 9 (2) 0.3 .274 2.1 6.1 
    BM fibrosis ≥ 1 0 (0)   
Death        
    No BM fibrosis 44 (10) 1.39 0.7 .545 2.3 11.3 21.8 
    BM fibrosis ≥ 1 5 (7) 1.02   5.3 5.3 12.6 
EventsNumber of events (%)Incidence per 100 patient-yearsIRRP5-year cumulative incidence, %10-year cumulative incidence, %15-year cumulative incidence, %
Thrombosis        
    No BM fibrosis 75 (17) 2.7 0.4 .03 14.6 20.3 32.0 
    BM fibrosis ≥ 1 5 (7) 1.1   1.8 14.1 20.3 
Progression to overt myelofibrosis        
    No BM fibrosis 25 (6) 0.8 2.7 .01 1.3 6.9 15.4 
    BM fibrosis ≥ 1 10 (14) 2.2   7.8 22.0 29.1 
Leukemic transformation        
    No BM fibrosis 9 (2) 0.3 .274 2.1 6.1 
    BM fibrosis ≥ 1 0 (0)   
Death        
    No BM fibrosis 44 (10) 1.39 0.7 .545 2.3 11.3 21.8 
    BM fibrosis ≥ 1 5 (7) 1.02   5.3 5.3 12.6 
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