Change in NFS after HCT stratified by patient characteristics
| Factor . | No. at HCT . | No. (%) evaluable for most recent NFS . | Time to most recent NFS, y, median (range) . | Change in NFS, IQR, median (range) . | P . |
|---|---|---|---|---|---|
| Overall | 60 | ||||
| Loes score at HCT | < .01 | ||||
| < 10 | 30 | 26 (87) | 2.9 (0.2-8.3) | 0 (−1 to 20), (0-1) | |
| ≥ 10 | 30 | 18 (60) | 2.1 (0.8-6.6) | 7.5 (0-23), (4-19) | |
| NFS at HCT | < .01 | ||||
| 0 | 23 | 20 (87) | 2.2 (0.2-8.3) | 0 (0-8), (0-0) | |
| ≥ 1 | 37 | 24 (65) | 2.3 (0.8-7.2) | 7 (−1 to 23), (1-17.5) | |
| Performance IQ at HCT | < .01 | ||||
| ≥ 80 | 29 | 23 (79) | 3.1 (0.5-8.5) | 0 (−1 to 22), (0-1) | |
| < 80 | 22 | 16 (73) | 1 (0.2-5.2) | 8 (0-23), (3-17.5) | |
| Full Scale IQ at HCT | < .01 | ||||
| ≥ 80 | 26 | 20 (77) | 3.5 (0.5-8.5) | 0 (−1 to 12), (0-1) | |
| < 80 | 20 | 14 (70) | 1 (0.2-5.2) | 11 (0-23), (2-20) | |
| Donor chimerism at day 60 | < .01 | ||||
| > 80% | 30 | 29 (97) | 3.1 (0.2-8.5) | 0 (−1 to 20), (0-7) | |
| ≤ 80% | 19 | 16 (84) | 0.5 (0.2-2) | 8 (0-23), (6-20.5) |
| Factor . | No. at HCT . | No. (%) evaluable for most recent NFS . | Time to most recent NFS, y, median (range) . | Change in NFS, IQR, median (range) . | P . |
|---|---|---|---|---|---|
| Overall | 60 | ||||
| Loes score at HCT | < .01 | ||||
| < 10 | 30 | 26 (87) | 2.9 (0.2-8.3) | 0 (−1 to 20), (0-1) | |
| ≥ 10 | 30 | 18 (60) | 2.1 (0.8-6.6) | 7.5 (0-23), (4-19) | |
| NFS at HCT | < .01 | ||||
| 0 | 23 | 20 (87) | 2.2 (0.2-8.3) | 0 (0-8), (0-0) | |
| ≥ 1 | 37 | 24 (65) | 2.3 (0.8-7.2) | 7 (−1 to 23), (1-17.5) | |
| Performance IQ at HCT | < .01 | ||||
| ≥ 80 | 29 | 23 (79) | 3.1 (0.5-8.5) | 0 (−1 to 22), (0-1) | |
| < 80 | 22 | 16 (73) | 1 (0.2-5.2) | 8 (0-23), (3-17.5) | |
| Full Scale IQ at HCT | < .01 | ||||
| ≥ 80 | 26 | 20 (77) | 3.5 (0.5-8.5) | 0 (−1 to 12), (0-1) | |
| < 80 | 20 | 14 (70) | 1 (0.2-5.2) | 11 (0-23), (2-20) | |
| Donor chimerism at day 60 | < .01 | ||||
| > 80% | 30 | 29 (97) | 3.1 (0.2-8.5) | 0 (−1 to 20), (0-7) | |
| ≤ 80% | 19 | 16 (84) | 0.5 (0.2-2) | 8 (0-23), (6-20.5) |
IQR indicates interquartile range.