Subject demographics and disposition
| Characteristic . | Dose groups . | Total (N = 16) . | |
|---|---|---|---|
| 25 IU/kg (n = 6) . | 65 IU/kg (n = 10) . | ||
| Mean age, y (minimum-maximum) | 40.3 (23-61) | 31.1 (23-42) | 34.6 (23-61) |
| Mean weight, kg (minimum-maximum) | 89.5 (73-105) | 78.7 (54-111) | 82.7 (54-111) |
| Ethnicity | |||
| White, n | 6 | 9 | 15 |
| Asian, n | 0 | 1 | 1 |
| Enrolled, n | 6 | 13 | 19 |
| Evaluated for safety, n | 6 | 10 | 16 |
| Included in PK analysis, n | 6 | 9 | 15 |
| Withdrawn before dosing, n | 0 | 3 | 3 |
| Characteristic . | Dose groups . | Total (N = 16) . | |
|---|---|---|---|
| 25 IU/kg (n = 6) . | 65 IU/kg (n = 10) . | ||
| Mean age, y (minimum-maximum) | 40.3 (23-61) | 31.1 (23-42) | 34.6 (23-61) |
| Mean weight, kg (minimum-maximum) | 89.5 (73-105) | 78.7 (54-111) | 82.7 (54-111) |
| Ethnicity | |||
| White, n | 6 | 9 | 15 |
| Asian, n | 0 | 1 | 1 |
| Enrolled, n | 6 | 13 | 19 |
| Evaluated for safety, n | 6 | 10 | 16 |
| Included in PK analysis, n | 6 | 9 | 15 |
| Withdrawn before dosing, n | 0 | 3 | 3 |